Effects of ZnO nanoparticles on antioxidant enzyme system of zebrafish embryos

Wen Jing Tian; Wei Bai; Chun Lu Zhao; Zhi Yong Zhang; Jun An Cui; Xiao He; Yu Hui Ma; Yu Liang Zhao

Effects of ZnO nanoparticles on antioxidant enzyme system of zebrafish embryos

Wen Jing Tian, Wei Bai, Chun Lu Zhao, Zhi Yong Zhang, Jun An Cui, Xiao He, Yu Hui Ma, Yu Liang Zhao

Houston Methodist

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

The toxicity effects of nano-ZnO suspension on antioxidant enzyme system of zebrafish embryos were investigated for evaluating its potential ecotoxicity. Exposure to nano-ZnO suspension led to the decrease in glutathione (GSH) content, the inhibition in catalase (CAT) and superoxidase dismutase (SOD) activity, and the increase in MDA level of zebrafish embryo.The result demonstrates that oxidative stress was one of the mechanisms of nano-ZnO ecotoxicity.

Original language	English (US)
Pages (from-to)	705-709
Number of pages	5
Journal	Zhongguo Huanjing Kexue/China Environmental Science
Volume	30
Issue number	5
State	Published - May 2010

Keywords

Oxidative damage
Zebrafish embryo
ZnO nanoparticle

ASJC Scopus subject areas

General Environmental Science

Cite this

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title = "Effects of ZnO nanoparticles on antioxidant enzyme system of zebrafish embryos",

abstract = "The toxicity effects of nano-ZnO suspension on antioxidant enzyme system of zebrafish embryos were investigated for evaluating its potential ecotoxicity. Exposure to nano-ZnO suspension led to the decrease in glutathione (GSH) content, the inhibition in catalase (CAT) and superoxidase dismutase (SOD) activity, and the increase in MDA level of zebrafish embryo.The result demonstrates that oxidative stress was one of the mechanisms of nano-ZnO ecotoxicity.",

keywords = "Oxidative damage, Zebrafish embryo, ZnO nanoparticle",

author = "Tian, {Wen Jing} and Wei Bai and Zhao, {Chun Lu} and Zhang, {Zhi Yong} and Cui, {Jun An} and Xiao He and Ma, {Yu Hui} and Zhao, {Yu Liang}",

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T1 - Effects of ZnO nanoparticles on antioxidant enzyme system of zebrafish embryos

AU - Tian, Wen Jing

AU - Bai, Wei

AU - Zhao, Chun Lu

AU - Zhang, Zhi Yong

AU - Cui, Jun An

AU - He, Xiao

AU - Ma, Yu Hui

AU - Zhao, Yu Liang

PY - 2010/5

Y1 - 2010/5

N2 - The toxicity effects of nano-ZnO suspension on antioxidant enzyme system of zebrafish embryos were investigated for evaluating its potential ecotoxicity. Exposure to nano-ZnO suspension led to the decrease in glutathione (GSH) content, the inhibition in catalase (CAT) and superoxidase dismutase (SOD) activity, and the increase in MDA level of zebrafish embryo.The result demonstrates that oxidative stress was one of the mechanisms of nano-ZnO ecotoxicity.

AB - The toxicity effects of nano-ZnO suspension on antioxidant enzyme system of zebrafish embryos were investigated for evaluating its potential ecotoxicity. Exposure to nano-ZnO suspension led to the decrease in glutathione (GSH) content, the inhibition in catalase (CAT) and superoxidase dismutase (SOD) activity, and the increase in MDA level of zebrafish embryo.The result demonstrates that oxidative stress was one of the mechanisms of nano-ZnO ecotoxicity.

KW - Oxidative damage

KW - Zebrafish embryo

KW - ZnO nanoparticle

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JF - Zhongguo Huanjing Kexue/China Environmental Science

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ER -

Effects of ZnO nanoparticles on antioxidant enzyme system of zebrafish embryos

Abstract

Keywords

ASJC Scopus subject areas

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