Effects of ZnO nanoparticles on antioxidant enzyme system of zebrafish embryos

Wen Jing Tian; Wei Bai; Chun Lu Zhao; Zhi Yong Zhang; Jun An Cui; Xiao He; Yu Hui Ma; Yu Liang Zhao

Effects of ZnO nanoparticles on antioxidant enzyme system of zebrafish embryos

Wen Jing Tian, Wei Bai, Chun Lu Zhao, Zhi Yong Zhang, Jun An Cui, Xiao He, Yu Hui Ma, Yu Liang Zhao

Research output: Contribution to journal › Article

Abstract

The toxicity effects of nano-ZnO suspension on antioxidant enzyme system of zebrafish embryos were investigated for evaluating its potential ecotoxicity. Exposure to nano-ZnO suspension led to the decrease in glutathione (GSH) content, the inhibition in catalase (CAT) and superoxidase dismutase (SOD) activity, and the increase in MDA level of zebrafish embryo.The result demonstrates that oxidative stress was one of the mechanisms of nano-ZnO ecotoxicity.

Original language	English (US)
Pages (from-to)	705-709
Number of pages	5
Journal	Zhongguo Huanjing Kexue/China Environmental Science
Volume	30
Issue number	5
State	Published - May 1 2010

Keywords

Oxidative damage
Zebrafish embryo
ZnO nanoparticle

ASJC Scopus subject areas

Environmental Science(all)

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abstract = "The toxicity effects of nano-ZnO suspension on antioxidant enzyme system of zebrafish embryos were investigated for evaluating its potential ecotoxicity. Exposure to nano-ZnO suspension led to the decrease in glutathione (GSH) content, the inhibition in catalase (CAT) and superoxidase dismutase (SOD) activity, and the increase in MDA level of zebrafish embryo.The result demonstrates that oxidative stress was one of the mechanisms of nano-ZnO ecotoxicity.",

keywords = "Oxidative damage, Zebrafish embryo, ZnO nanoparticle",

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T1 - Effects of ZnO nanoparticles on antioxidant enzyme system of zebrafish embryos

AU - Tian, Wen Jing

AU - Bai, Wei

AU - Zhao, Chun Lu

AU - Zhang, Zhi Yong

AU - Cui, Jun An

AU - He, Xiao

AU - Ma, Yu Hui

AU - Zhao, Yu Liang

PY - 2010/5/1

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N2 - The toxicity effects of nano-ZnO suspension on antioxidant enzyme system of zebrafish embryos were investigated for evaluating its potential ecotoxicity. Exposure to nano-ZnO suspension led to the decrease in glutathione (GSH) content, the inhibition in catalase (CAT) and superoxidase dismutase (SOD) activity, and the increase in MDA level of zebrafish embryo.The result demonstrates that oxidative stress was one of the mechanisms of nano-ZnO ecotoxicity.

AB - The toxicity effects of nano-ZnO suspension on antioxidant enzyme system of zebrafish embryos were investigated for evaluating its potential ecotoxicity. Exposure to nano-ZnO suspension led to the decrease in glutathione (GSH) content, the inhibition in catalase (CAT) and superoxidase dismutase (SOD) activity, and the increase in MDA level of zebrafish embryo.The result demonstrates that oxidative stress was one of the mechanisms of nano-ZnO ecotoxicity.

KW - Oxidative damage

KW - Zebrafish embryo

KW - ZnO nanoparticle

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