Effects of polychlorinated dibenzofurans on compounds in hepatic DNA of female Sprague-Dawley rats: Structure dependence and mechanistic considerations

Keyphrases

• Sprague-Dawley Rats 100%
• Polychlorinated Dibenzo-p-dioxins 100%
• PeCDF 100%
• Mechanistic Considerations 100%
• Structure Dependence 100%
• Ah Receptor 66%
• 2,3,4,7,8-PeCDF 50%
• Liver 33%
• 2,3,7,8-tetrachlorodibenzo-p-dioxin 33%
• Receptor Agonist 33%
• Structure-dependent 33%
• Tumor Promotion 33%
• Cytochrome P450 (CYP450) 16%
• Phenobarbital 16%
• Oncogenesis 16%
• Inducer 16%
• Age-dependent 16%
• Observed Effects 16%
• Target Organ 16%
• Carcinogen 16%
• Aryl Hydrocarbon Hydroxylases 16%
• Tumor Promoter 16%
• Receptor-mediated 16%
• Structure-activity Relationship 16%
• Agonist Activity 16%
• Chemical Structure 16%
• DNA Modification 16%
• Biochemical Properties 16%
• Receptor Binding Affinity 16%
• Enzyme Induction 16%
• 32P-postlabeling Assay 16%
• DNA nucleotides 16%
• Toxic Properties 16%
• Carcinogen-DNA Adduct 16%
• Compound Patterns 16%
• Compound Formation 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Aromatic Hydrocarbon Receptor 100%
• Sprague Dawley Rat 100%
• Polychlorinated Dibenzofuran 100%
• 2,3,7,8-Tetrachlorodibenzodioxin 50%
• Receptor Agonist 50%
• Carcinogen 50%
• Tumor Promotion 50%
• Phenobarbital 25%
• Cytochrome P450 25%
• Carcinogenesis 25%
• Unspecific Monooxygenase 25%
• Tumor Promoter 25%
• Biological Marker 25%
• Structure Activity Relationship 25%
• Phosphorus 32 25%
• Enzyme Induction 25%