Effects of acute lanthanum exposure on calcium absorption in rats

X. He, Z. Y. Zhang, L. X. Feng, Z. J. Li, J. H. Yang, Y. L. Zhao, Z. F. Chai

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

After an acute exposure to lanthanum chloride, the pharmacokinetics of calcium uptake in rats was studied by radioactive 47Ca tracer. The accumulated doses of calcium in the left femurs during 24 hours were determined. The results showed that the area under the curves (AUC), specific activity of maximal blood 47Ca concentration (C max ), distribution rate constant (K a ) and the accumulated dose of calcium in the left femur decreased while time to C max (T peak ) increased with the rising dosage of lanthanum exposure. It indicated that lanthanum expose had a negative effect on calcium absorption.

Original languageEnglish (US)
Pages (from-to)557-559
Number of pages3
JournalJournal of Radioanalytical and Nuclear Chemistry
Volume272
Issue number3
DOIs
StatePublished - Jun 2007

ASJC Scopus subject areas

  • Analytical Chemistry
  • Nuclear Energy and Engineering
  • Radiology Nuclear Medicine and imaging
  • Pollution
  • Spectroscopy
  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

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