Effectiveness of Bariatric Surgery in Increasing Kidney Transplant Eligibility in Patients with Kidney Failure Requiring Dialysis

Basem G. Soliman, Nabil Tariq, Yi Ying Law, Stephanie Yi, Nwabunie Nwana, Rita Bosetti, Bita Kash, Linda W. Moore, A. Osama Gaber, Vadim Sherman

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Purpose: Severe obesity can increase risk of complications after kidney transplantation. There is a paucity of literature on bariatric surgery outcomes in renal transplant candidates. The objective of this study was to analyze outcomes of bariatric surgery as a weight reduction strategy for patients with kidney failure to enhance eligibility for kidney transplantation. Materials and Methods: We performed a retrospective analysis of the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program database at a single institution for patients with chronic kidney disease receiving hemodialysis therapy (CKD G5D) undergoing bariatric surgery between 2011 and 2018. Results: Of 2363 patients who underwent bariatric surgery, 38 (1.6%) had CKD G5D; median age (range) was 49 years (33; 69), 52.6% were female, and mean BMI was 44.2 kg/m2. Twenty-four patients underwent laparoscopic Roux-en-Y gastric bypass (LRYGB), and 14 patients underwent laparoscopic sleeve gastrectomy. Seventeen patients (46%, n=37) had a BMI≤35 at 6 months, while 25 patients (75.8%, n=33) achieved a BMI≤35 at 12 months. Of these, 18 patients (47%) were listed for kidney transplant, and 8 patients (21%) received kidney transplant. There was no statistically significant difference between sleeve and LRYGB procedures in patients who reached BMI of 35 at 12 months (P=0.58). Median length of stay was 2.3 days. Thirty-day readmission rate was 2 patients (5.3%), and 2 patients (5.3%) required reoperation (one for bleeding, one for acute recurrent hiatal hernia). No mortality occurred. Conclusion: Laparoscopic bariatric surgery offers effective weight loss for CKD G5D patients to achieve transplant eligibility with acceptable outcomes. Graphical abstract: [Figure not available: see fulltext.]

Original languageEnglish (US)
Pages (from-to)3436-3443
Number of pages8
JournalObesity Surgery
Volume31
Issue number8
DOIs
StatePublished - Aug 2021

Keywords

  • Bariatric surgery
  • Gastric bypass
  • Hemodialysis
  • Kidney transplantation
  • Laparoscopic sleeve gastrectomy
  • Bariatric Surgery
  • Gastric Bypass
  • Humans
  • Middle Aged
  • Treatment Outcome
  • Kidney Transplantation
  • Laparoscopy
  • Gastrectomy
  • Obesity, Morbid/surgery
  • Renal Insufficiency
  • Female
  • Retrospective Studies
  • Postoperative Complications
  • Renal Dialysis

ASJC Scopus subject areas

  • Nutrition and Dietetics
  • Surgery
  • Endocrinology, Diabetes and Metabolism

Fingerprint

Dive into the research topics of 'Effectiveness of Bariatric Surgery in Increasing Kidney Transplant Eligibility in Patients with Kidney Failure Requiring Dialysis'. Together they form a unique fingerprint.

Cite this