Effect of penetrating keratoplasty using grafts of various sizes on keratoconic myopia and astigmatism

Louis J. Girard, Ismael Eguez, Nestor F. Esnaola, Laura Barnett, Akef Maghraby

Research output: Contribution to journalArticlepeer-review

31 Scopus citations


The records of 72 consecutive keratoconic eyes undergoing penetrating keratoplasty were reviewed for changes in myopia and astigmatism. Ages of the patients averaged 32.7 years. All sutures were removed after three months. Follow-up average was 40.2 months. Results showed an average decrease in myopia of 6.63 diopters (D) in 60 eyes (82.86%a) and an average increase in myopia of 1.88 D in 12 of 70 eyes (17.14%). The decrease/increase in myopia and postoperative astigmatism was compared for grafts equal to the opening, grafts smaller than the opening, and grafts larger than the opening. The largest average decrease in myopia was 13.86 D (range 6.63 to 20.00), which occurred when a graft smaller than the opening was used (P < .01). This group also showed the least postoperative astigmatism (2.82 D) (P < .01). From this study, it appears that the use of a graft 0.25 mm smaller than the trephine opening in the host (i.e., 7.50 mm graft/7.75 mm opening) for penetrating keratoplasty in keratoconus is justified. A prospective study is now in progress.

Original languageEnglish (US)
Pages (from-to)541-547
Number of pages7
JournalJournal of Cataract and Refractive Surgery
Issue number5
StatePublished - Jan 1 1988


  • disparate graft/opening
  • fresh eves vs. M-K preserved corneas
  • keratoconus
  • penetrating keratoplasty
  • postoperative astigmatism
  • postoperative myopia

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology
  • Sensory Systems


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