Effect of intraarticular stainless steel implants on the health of the rabbit knee joint: An experimental study

Malcolm Stubbs; Hong Zhang; Mark S. Vrahas; Richard V. Baratta; Arthur W. Zieske

doi:10.1097/00005131-200011000-00009

Effect of intraarticular stainless steel implants on the health of the rabbit knee joint: An experimental study

Malcolm Stubbs, Hong Zhang, Mark S. Vrahas, Richard V. Baratta, Arthur W. Zieske

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Objective: This study was designed to investigate the histologic changes to the knee joints of rabbits after insertion of a metal implant in retrograde fashion. Design: Eighteen rabbits had a modified stainless steel screw implanted in one knee, with the other knee serving as a sham-operated control. The animals were killed after two, six, or twelve months. Outcome Measures: The histologic status of the cartilage and synovium were graded by the Modified Mankin and Mirra criteria, respectively. Results: At the time of killing, every insertion site was covered by fibrous tissue. Statistical analysis showed no significant differences in histologic scores between implanted and control knees. Conclusions: Insertion of a stable, well-fixed implant results in no deleterious effect to the knee joint.

Original language	English (US)
Pages (from-to)	567-570
Number of pages	4
Journal	Journal of orthopaedic trauma
Volume	14
Issue number	8
DOIs	https://doi.org/10.1097/00005131-200011000-00009
State	Published - Jan 1 2000

Keywords

Internal fixation
Metallosis
Retrograde nails

ASJC Scopus subject areas

Surgery
Orthopedics and Sports Medicine

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10.1097/00005131-200011000-00009

Cite this

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title = "Effect of intraarticular stainless steel implants on the health of the rabbit knee joint: An experimental study",

abstract = "Objective: This study was designed to investigate the histologic changes to the knee joints of rabbits after insertion of a metal implant in retrograde fashion. Design: Eighteen rabbits had a modified stainless steel screw implanted in one knee, with the other knee serving as a sham-operated control. The animals were killed after two, six, or twelve months. Outcome Measures: The histologic status of the cartilage and synovium were graded by the Modified Mankin and Mirra criteria, respectively. Results: At the time of killing, every insertion site was covered by fibrous tissue. Statistical analysis showed no significant differences in histologic scores between implanted and control knees. Conclusions: Insertion of a stable, well-fixed implant results in no deleterious effect to the knee joint.",

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T1 - Effect of intraarticular stainless steel implants on the health of the rabbit knee joint

T2 - An experimental study

AU - Stubbs, Malcolm

AU - Zhang, Hong

AU - Vrahas, Mark S.

AU - Baratta, Richard V.

AU - Zieske, Arthur W.

PY - 2000/1/1

Y1 - 2000/1/1

N2 - Objective: This study was designed to investigate the histologic changes to the knee joints of rabbits after insertion of a metal implant in retrograde fashion. Design: Eighteen rabbits had a modified stainless steel screw implanted in one knee, with the other knee serving as a sham-operated control. The animals were killed after two, six, or twelve months. Outcome Measures: The histologic status of the cartilage and synovium were graded by the Modified Mankin and Mirra criteria, respectively. Results: At the time of killing, every insertion site was covered by fibrous tissue. Statistical analysis showed no significant differences in histologic scores between implanted and control knees. Conclusions: Insertion of a stable, well-fixed implant results in no deleterious effect to the knee joint.

AB - Objective: This study was designed to investigate the histologic changes to the knee joints of rabbits after insertion of a metal implant in retrograde fashion. Design: Eighteen rabbits had a modified stainless steel screw implanted in one knee, with the other knee serving as a sham-operated control. The animals were killed after two, six, or twelve months. Outcome Measures: The histologic status of the cartilage and synovium were graded by the Modified Mankin and Mirra criteria, respectively. Results: At the time of killing, every insertion site was covered by fibrous tissue. Statistical analysis showed no significant differences in histologic scores between implanted and control knees. Conclusions: Insertion of a stable, well-fixed implant results in no deleterious effect to the knee joint.

KW - Internal fixation

KW - Metallosis

KW - Retrograde nails

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Effect of intraarticular stainless steel implants on the health of the rabbit knee joint: An experimental study

Abstract

Keywords

ASJC Scopus subject areas

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