Effect of intraarticular stainless steel implants on the health of the rabbit knee joint: An experimental study

Malcolm Stubbs, Hong Zhang, Mark S. Vrahas, Richard V. Baratta, Arthur W. Zieske

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Objective: This study was designed to investigate the histologic changes to the knee joints of rabbits after insertion of a metal implant in retrograde fashion. Design: Eighteen rabbits had a modified stainless steel screw implanted in one knee, with the other knee serving as a sham-operated control. The animals were killed after two, six, or twelve months. Outcome Measures: The histologic status of the cartilage and synovium were graded by the Modified Mankin and Mirra criteria, respectively. Results: At the time of killing, every insertion site was covered by fibrous tissue. Statistical analysis showed no significant differences in histologic scores between implanted and control knees. Conclusions: Insertion of a stable, well-fixed implant results in no deleterious effect to the knee joint.

Original languageEnglish (US)
Pages (from-to)567-570
Number of pages4
JournalJournal of orthopaedic trauma
Volume14
Issue number8
DOIs
StatePublished - Jan 1 2000

Keywords

  • Internal fixation
  • Metallosis
  • Retrograde nails

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

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