Objective: This study was designed to investigate the histologic changes to the knee joints of rabbits after insertion of a metal implant in retrograde fashion. Design: Eighteen rabbits had a modified stainless steel screw implanted in one knee, with the other knee serving as a sham-operated control. The animals were killed after two, six, or twelve months. Outcome Measures: The histologic status of the cartilage and synovium were graded by the Modified Mankin and Mirra criteria, respectively. Results: At the time of killing, every insertion site was covered by fibrous tissue. Statistical analysis showed no significant differences in histologic scores between implanted and control knees. Conclusions: Insertion of a stable, well-fixed implant results in no deleterious effect to the knee joint.
- Internal fixation
- Retrograde nails
ASJC Scopus subject areas
- Orthopedics and Sports Medicine