Effect of hemodynamic factors on atherosclerosis in the abdominal aorta

Nghia D. Nguyen, Abida Haque

Research output: Contribution to journalArticle

46 Scopus citations

Abstract

Thi distribution pattern of atherosclerotic plaques in the human abdominal aorta is examined using autopsy specimens. The location of the plaques is found to be dominant where flow separation may occur in the abdominal aorta based on hemodynamic theory. This observation provides strong support for the role of flow separation with subsequent platelet aggregation in atherogenesis. The severity of plaque formed in the anterior inferior wall of the abdominal aorta is found to be affected by the branching angles of the renal arteries as deduced from experimental results using glass tube models.

Original languageEnglish (US)
Pages (from-to)33-39
Number of pages7
JournalAtherosclerosis
Volume84
Issue number1
DOIs
StatePublished - Jan 1 1990

Keywords

  • Atherosclerosis
  • Flow separation
  • Hemodynamics
  • Thrombus

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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