Effect of glucagon-like peptide-1 receptor agonists on major adverse cardiovascular events in patients with inflammatory bowel disease

Michael Saadeh; Apoorva Krishna Chandar; Sadeer Al-Kindi; Vu Quang Nguyen; Revital Gorodeski Baskin; Jeffry Katz; Fabio Cominelli; Miguel Regueiro; Emad Mansoor

doi:10.1093/crocol/otaf056

Effect of glucagon-like peptide-1 receptor agonists on major adverse cardiovascular events in patients with inflammatory bowel disease

Michael Saadeh, Apoorva Krishna Chandar, Sadeer Al-Kindi, Vu Quang Nguyen, Revital Gorodeski Baskin, Jeffry Katz, Fabio Cominelli, Miguel Regueiro, Emad Mansoor

Research output: Contribution to journal › Review article › peer-review

Abstract

Patients with IBD are at an increased risk of major adverse cardiovascular events (MACE), potentially due to both atherosclerotic and non-atherosclerotic, inflammation- mediated pathways. In this retrospective cohort study, IBD patients with GLP-1RA use were less likely to have MACE.

Original language	English (US)
Article number	otaf056
Journal	Crohn's and Colitis 360
Volume	7
Issue number	3
DOIs	https://doi.org/10.1093/crocol/otaf056
State	Published - Jul 1 2025

ASJC Scopus subject areas

Gastroenterology

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10.1093/crocol/otaf056

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title = "Effect of glucagon-like peptide-1 receptor agonists on major adverse cardiovascular events in patients with inflammatory bowel disease",

abstract = "Patients with IBD are at an increased risk of major adverse cardiovascular events (MACE), potentially due to both atherosclerotic and non-atherosclerotic, inflammation- mediated pathways. In this retrospective cohort study, IBD patients with GLP-1RA use were less likely to have MACE.",

author = "Michael Saadeh and Chandar, \{Apoorva Krishna\} and Sadeer Al-Kindi and Nguyen, \{Vu Quang\} and Baskin, \{Revital Gorodeski\} and Jeffry Katz and Fabio Cominelli and Miguel Regueiro and Emad Mansoor",

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doi = "10.1093/crocol/otaf056",

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AU - Saadeh, Michael

AU - Chandar, Apoorva Krishna

AU - Al-Kindi, Sadeer

AU - Nguyen, Vu Quang

AU - Baskin, Revital Gorodeski

AU - Katz, Jeffry

AU - Cominelli, Fabio

AU - Regueiro, Miguel

AU - Mansoor, Emad

PY - 2025/7/1

Y1 - 2025/7/1

N2 - Patients with IBD are at an increased risk of major adverse cardiovascular events (MACE), potentially due to both atherosclerotic and non-atherosclerotic, inflammation- mediated pathways. In this retrospective cohort study, IBD patients with GLP-1RA use were less likely to have MACE.

AB - Patients with IBD are at an increased risk of major adverse cardiovascular events (MACE), potentially due to both atherosclerotic and non-atherosclerotic, inflammation- mediated pathways. In this retrospective cohort study, IBD patients with GLP-1RA use were less likely to have MACE.

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U2 - 10.1093/crocol/otaf056

DO - 10.1093/crocol/otaf056

M3 - Review article

AN - SCOPUS:105015197934

SN - 2631-827X

VL - 7

JO - Crohn's and Colitis 360

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M1 - otaf056

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Effect of glucagon-like peptide-1 receptor agonists on major adverse cardiovascular events in patients with inflammatory bowel disease

Abstract

ASJC Scopus subject areas

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