Effect of extended cross-clamp time during thoracoabdominal aortic aneurysm repair

Hazim J. Safi, Anders Winnerkvist, Charles C. Miller, Dimitrios C. Iliopoulos, Michael J. Reardon, Rafael Espada, John C. Baldwin

Research output: Contribution to journalArticlepeer-review

102 Scopus citations


Background. In previous studies of the neurologic outcome of patients undergoing thoracoabdominal aortic aneurysm repair with the simple cross- clamp technique, cross-clamp time of greater than 30 minutes was identified as an important risk factor. We retrospectively examined the effect of damp time of 30 minutes or greater on outcome for patients undergoing repair with the addition of surgical adjuncts. Methods. Between February 1991 and June 1996 we operated on 370 patients for thoracoabdominal or descending thoracic aortic aneurysm. Two hundred seventy-one of these patients with cross-clamp times of 30 minutes or greater were included in this study. One hundred twelve patients underwent simple cross-clamp repair, whereas 159 were operated on with the surgical adjuncts of distal aortic perfusion and cerebrospinal fluid drainage. Results. By multivariate analysis, acute dissection, surgical adjuncts, and aneurysm extent proved most significant in overall patient outcome. The overall rate of early neurologic deficits was 23 of 271 (8.5%). For highest risk patients with type II thoracoabdominal aortic aneurysms, the rate of neurologic deficits was 11 of 29 (38%) for cross- clamp versus 6 of 82 (7.3%) for adjunct operation patients (odds ratio = 0.13; p < 0.001). Conclusions. The adjuncts of cerebrospinal fluid drainage and distal aortic perfusion decreased the risk of extended cross-clamp time during thoracoabdominal aortic aneurysm repair, particularly for highest risk type II.

Original languageEnglish (US)
Pages (from-to)1204-1208
Number of pages5
JournalAnnals of Thoracic Surgery
Issue number4
StatePublished - Oct 1998

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine


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