Abstract
The effect of endotoxin on the growth and morphology of cultured chinchilla middle ear epithelium was examined. Within 24 hours of culture, cells maintained in medium containing endotoxin exhibited dose-dependent morphological changes. The highest concentration of endotoxin (100 mg) resulted in cell death. The growth curve of the cells in culture demonstrated a dose-dependent, significant increase in cell number when endotoxin was added to the medium.
Original language | English (US) |
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Pages (from-to) | 607-611 |
Number of pages | 5 |
Journal | Annals of Otology, Rhinology & Laryngology |
Volume | 101 |
Issue number | 7 |
DOIs | |
State | Published - Jul 1992 |
Keywords
- cell culture
- endotoxin
- middle ear epithelium
ASJC Scopus subject areas
- Otorhinolaryngology