Effect of endotoxin on cultured chinchilla middle ear epithelium

Akihiko Nakamura, Clemens Van Bliterswijk, Thomas F. Demaria, David J. Lim

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

The effect of endotoxin on the growth and morphology of cultured chinchilla middle ear epithelium was examined. Within 24 hours of culture, cells maintained in medium containing endotoxin exhibited dose-dependent morphological changes. The highest concentration of endotoxin (100 mg) resulted in cell death. The growth curve of the cells in culture demonstrated a dose-dependent, significant increase in cell number when endotoxin was added to the medium.

Original languageEnglish (US)
Pages (from-to)607-611
Number of pages5
JournalAnnals of Otology, Rhinology & Laryngology
Volume101
Issue number7
DOIs
StatePublished - Jul 1992

Keywords

  • cell culture
  • endotoxin
  • middle ear epithelium

ASJC Scopus subject areas

  • Otorhinolaryngology

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