Effect of endotoxin on cultured chinchilla middle ear epithelium

Akihiko Nakamura; Clemens Van Bliterswijk; Thomas F. Demaria; David J. Lim

doi:10.1177/000348949210100712

Effect of endotoxin on cultured chinchilla middle ear epithelium

Akihiko Nakamura, Clemens Van Bliterswijk, Thomas F. Demaria, David J. Lim

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

The effect of endotoxin on the growth and morphology of cultured chinchilla middle ear epithelium was examined. Within 24 hours of culture, cells maintained in medium containing endotoxin exhibited dose-dependent morphological changes. The highest concentration of endotoxin (100 mg) resulted in cell death. The growth curve of the cells in culture demonstrated a dose-dependent, significant increase in cell number when endotoxin was added to the medium.

Original language	English (US)
Pages (from-to)	607-611
Number of pages	5
Journal	Annals of Otology, Rhinology & Laryngology
Volume	101
Issue number	7
DOIs	https://doi.org/10.1177/000348949210100712
State	Published - Jul 1992

Keywords

cell culture
endotoxin
middle ear epithelium

ASJC Scopus subject areas

Otorhinolaryngology

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10.1177/000348949210100712

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title = "Effect of endotoxin on cultured chinchilla middle ear epithelium",

abstract = "The effect of endotoxin on the growth and morphology of cultured chinchilla middle ear epithelium was examined. Within 24 hours of culture, cells maintained in medium containing endotoxin exhibited dose-dependent morphological changes. The highest concentration of endotoxin (100 mg) resulted in cell death. The growth curve of the cells in culture demonstrated a dose-dependent, significant increase in cell number when endotoxin was added to the medium.",

keywords = "cell culture, endotoxin, middle ear epithelium",

author = "Akihiko Nakamura and {Van Bliterswijk}, Clemens and Demaria, {Thomas F.} and Lim, {David J.}",

year = "1992",

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T1 - Effect of endotoxin on cultured chinchilla middle ear epithelium

AU - Nakamura, Akihiko

AU - Van Bliterswijk, Clemens

AU - Demaria, Thomas F.

AU - Lim, David J.

PY - 1992/7

Y1 - 1992/7

N2 - The effect of endotoxin on the growth and morphology of cultured chinchilla middle ear epithelium was examined. Within 24 hours of culture, cells maintained in medium containing endotoxin exhibited dose-dependent morphological changes. The highest concentration of endotoxin (100 mg) resulted in cell death. The growth curve of the cells in culture demonstrated a dose-dependent, significant increase in cell number when endotoxin was added to the medium.

AB - The effect of endotoxin on the growth and morphology of cultured chinchilla middle ear epithelium was examined. Within 24 hours of culture, cells maintained in medium containing endotoxin exhibited dose-dependent morphological changes. The highest concentration of endotoxin (100 mg) resulted in cell death. The growth curve of the cells in culture demonstrated a dose-dependent, significant increase in cell number when endotoxin was added to the medium.

KW - cell culture

KW - endotoxin

KW - middle ear epithelium

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U2 - 10.1177/000348949210100712

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JO - Annals of Otology, Rhinology and Laryngology

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SN - 0003-4894

IS - 7

ER -

Effect of endotoxin on cultured chinchilla middle ear epithelium

Abstract

Keywords

ASJC Scopus subject areas

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