[Effect of Campath-1H induction on immunosuppression in small intestine transplantation].

Jian Zhou, Wei Qiang Ju, Xiao Shun He, Dong Ping Wang, Xiao Feng Zhu, Lin Wei Wu, Qiang Tai, Y. Ma, An Bin Hu, Guo Dong Wang, Jie Fu Huang

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


To investigate the effect of Campath-1H induction on immunosuppression in small intestine transplantation. Clinical data of a patient who underwent small intestine transplantation were retrospectively summarized. Intraoperative Campath-1H induction by intravenous injection was administered. Triple immunosuppression(FK506, MMF and methylprednisolone) was used postoperatively. The lymphocyte and leukocyte decreased significantly following Campath-1H induction, and returned to normal after adjusting the dose of immunosuppressant and use of colony stimulating factor. There were no acute rejection, graft versus host disease, or severe infection during the immediate postoperative period. The patient recovered and discharged. Intraoperative Campath-1H induction and postoperative triple immunosuppression using FK506, MMF, and methylprednisolone may prevent rejection and graft versus host disease in the early stage after small intestine transplantation.

Original languageEnglish (US)
Pages (from-to)199-201
Number of pages3
JournalZhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
Issue number3
StatePublished - Mar 2011

ASJC Scopus subject areas

  • Medicine(all)


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