Effect of Benzo[a]Pyrene on Spindle Misorientation and Fidelity of Chromosome Segregation in Lung Epithelial BEAS-2B Cells

Keyphrases

• Benzo(a)pyrene 100%
• Chromosome Segregation 100%
• Lung Epithelial 100%
• BEAS-2B Cells 100%
• Spindle Misorientation 100%
• DNA Damage 42%
• Genomic Instability 42%
• Mitotic Abnormalities 28%
• Chromosome Missegregation 28%
• Lung 14%
• Cigarette Smokers 14%
• Associated Genes 14%
• Signaling Cascades 14%
• Tobacco Smoke 14%
• Genome Analysis 14%
• Mitotic Spindle 14%
• Healthy Lung 14%
• DNA Adducts 14%
• B(a)P 14%
• Aneuploidy 14%
• Lung Epithelial Cells 14%
• Human Bronchial Epithelial Cells 14%
• Confocal Imaging 14%
• Mitotic Apparatus 14%
• Centriole Duplication 14%
• H2AX 14%
• Environmental Carcinogens 14%
• Polo-like Kinase 1 (PLK1) 14%
• BEAS-2B 14%
• Spindle Formation 14%
• Bipolar Spindle 14%
• Mitotic Spindle Apparatus 14%
• Spindle Dynamics 14%
• Centriole Disengagement 14%

Biochemistry, Genetics and Molecular Biology

• DNA Damage 100%
• Chromosome Segregation 100%
• P53 66%
• P21 66%
• Genome Instability 66%
• Mitosis Spindle 66%
• Dynamics 33%
• Downregulation 33%
• Comparative Genomics 33%
• Centrosome 33%
• DNA Adduct 33%
• Aneuploidy 33%
• Cigarette Smoking 33%
• Confocal Microscopy 33%
• Centriole 33%
• Multipolar Spindles 33%
• Genomic Instability 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Benzo(a)pyrene 100%
• Protein P53 28%
• Prematurity 14%
• Carcinogen 14%
• Aneuploidy 14%
• Confocal Microscopy 14%