Early descriptions of Parkinson disease in ancient China

Zhen Xin Zhang; Zhen Hua Dong; Gustavo C. Román

doi:10.1001/archneur.63.5.782

Early descriptions of Parkinson disease in ancient China

Zhen Xin Zhang, Zhen Hua Dong, Gustavo C. Román

Research output: Contribution to journal › Review article › peer-review

33 Scopus citations

Abstract

A historical search of traditional Chinese medical sources revealed several ancient descriptions suggestive of Parkinson disease dating back to 425 BC. Zhang Zihe (1156-1228) provided the first description of a typical case of Parkinson disease in the book Ru Men Shi Qin. Traditional Chinese medicine also recommended an "antitremor pill" that to this day appears to provide reasonable symptomatic treatment for tremor and rigidity. Based on this evidence, we conclude that Parkinson disease (PD) was first described more than 2400 years ago in China.

Original language	English (US)
Pages (from-to)	782-784
Number of pages	3
Journal	Archives of neurology
Volume	63
Issue number	5
DOIs	https://doi.org/10.1001/archneur.63.5.782
State	Published - May 2006

ASJC Scopus subject areas

Arts and Humanities (miscellaneous)
Clinical Neurology

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abstract = "A historical search of traditional Chinese medical sources revealed several ancient descriptions suggestive of Parkinson disease dating back to 425 BC. Zhang Zihe (1156-1228) provided the first description of a typical case of Parkinson disease in the book Ru Men Shi Qin. Traditional Chinese medicine also recommended an {"}antitremor pill{"} that to this day appears to provide reasonable symptomatic treatment for tremor and rigidity. Based on this evidence, we conclude that Parkinson disease (PD) was first described more than 2400 years ago in China.",

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AB - A historical search of traditional Chinese medical sources revealed several ancient descriptions suggestive of Parkinson disease dating back to 425 BC. Zhang Zihe (1156-1228) provided the first description of a typical case of Parkinson disease in the book Ru Men Shi Qin. Traditional Chinese medicine also recommended an "antitremor pill" that to this day appears to provide reasonable symptomatic treatment for tremor and rigidity. Based on this evidence, we conclude that Parkinson disease (PD) was first described more than 2400 years ago in China.

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Early descriptions of Parkinson disease in ancient China

Abstract

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