Dynamic fast‐atom bombardment mass spectrometry of conjugated metabolites of benzo[a]pyrene

Yang Yang; Börje Egestad; Bengt Jernström; Jan Sjöovall; Jan‐Åke Gustafsson; Joseph Rafter; T. A. Bailli

doi:10.1002/rcm.1290051103

Dynamic fast‐atom bombardment mass spectrometry of conjugated metabolites of benzo[a]pyrene

Yang Yang, Börje Egestad, Bengt Jernström, Jan Sjöovall, Jan‐Åke Gustafsson, Joseph Rafter, T. A. Bailli

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

The N‐acetylcysteine, cysteine and gluathione conjugates of r‐7,t‐8‐dihydroxy‐t‐9,10‐oxy‐7,8,9,10‐tetrahydrobenzo[a]pyrene as well as sulphuric and glucuronic acid conjugates of hydroxybenzo[a]pyrenes have been studied by fast‐atom bombardment mass spectrometry (FABMS). Dynamic FABMS has been shown to be advantageous over conventional static FABMS giving more intense spectra with less material in both positive‐and negative‐ion modes. The spectra show quasmolecular ions and fragment ions indicative of the aglycome and/or the conjugating group.

Original language	English (US)
Pages (from-to)	499-502
Number of pages	4
Journal	Rapid Communications in Mass Spectrometry
Volume	5
Issue number	11
DOIs	https://doi.org/10.1002/rcm.1290051103
State	Published - Nov 1991

ASJC Scopus subject areas

Analytical Chemistry
Spectroscopy
Organic Chemistry

Access to Document

10.1002/rcm.1290051103

Cite this

@article{c434ee6aaff440c28a527625c3e0e64f,

title = "Dynamic fast‐atom bombardment mass spectrometry of conjugated metabolites of benzo[a]pyrene",

abstract = "The N‐acetylcysteine, cysteine and gluathione conjugates of r‐7,t‐8‐dihydroxy‐t‐9,10‐oxy‐7,8,9,10‐tetrahydrobenzo[a]pyrene as well as sulphuric and glucuronic acid conjugates of hydroxybenzo[a]pyrenes have been studied by fast‐atom bombardment mass spectrometry (FABMS). Dynamic FABMS has been shown to be advantageous over conventional static FABMS giving more intense spectra with less material in both positive‐and negative‐ion modes. The spectra show quasmolecular ions and fragment ions indicative of the aglycome and/or the conjugating group.",

author = "Yang Yang and B{\"o}rje Egestad and Bengt Jernstr{\"o}m and Jan Sj{\"o}ovall and Jan‐{\AA}ke Gustafsson and Joseph Rafter and Bailli, \{T. A.\}",

year = "1991",

month = nov,

doi = "10.1002/rcm.1290051103",

language = "English (US)",

volume = "5",

pages = "499--502",

journal = "Rapid Communications in Mass Spectrometry",

issn = "0951-4198",

publisher = "Wiley",

number = "11",

}

TY - JOUR

T1 - Dynamic fast‐atom bombardment mass spectrometry of conjugated metabolites of benzo[a]pyrene

AU - Yang, Yang

AU - Egestad, Börje

AU - Jernström, Bengt

AU - Sjöovall, Jan

AU - Gustafsson, Jan‐Åke

AU - Rafter, Joseph

AU - Bailli, T. A.

PY - 1991/11

Y1 - 1991/11

N2 - The N‐acetylcysteine, cysteine and gluathione conjugates of r‐7,t‐8‐dihydroxy‐t‐9,10‐oxy‐7,8,9,10‐tetrahydrobenzo[a]pyrene as well as sulphuric and glucuronic acid conjugates of hydroxybenzo[a]pyrenes have been studied by fast‐atom bombardment mass spectrometry (FABMS). Dynamic FABMS has been shown to be advantageous over conventional static FABMS giving more intense spectra with less material in both positive‐and negative‐ion modes. The spectra show quasmolecular ions and fragment ions indicative of the aglycome and/or the conjugating group.

AB - The N‐acetylcysteine, cysteine and gluathione conjugates of r‐7,t‐8‐dihydroxy‐t‐9,10‐oxy‐7,8,9,10‐tetrahydrobenzo[a]pyrene as well as sulphuric and glucuronic acid conjugates of hydroxybenzo[a]pyrenes have been studied by fast‐atom bombardment mass spectrometry (FABMS). Dynamic FABMS has been shown to be advantageous over conventional static FABMS giving more intense spectra with less material in both positive‐and negative‐ion modes. The spectra show quasmolecular ions and fragment ions indicative of the aglycome and/or the conjugating group.

UR - https://www.scopus.com/pages/publications/84990655591

UR - https://www.scopus.com/inward/citedby.url?scp=84990655591&partnerID=8YFLogxK

U2 - 10.1002/rcm.1290051103

DO - 10.1002/rcm.1290051103

M3 - Article

AN - SCOPUS:84990655591

SN - 0951-4198

VL - 5

SP - 499

EP - 502

JO - Rapid Communications in Mass Spectrometry

JF - Rapid Communications in Mass Spectrometry

IS - 11

ER -

Dynamic fast‐atom bombardment mass spectrometry of conjugated metabolites of benzo[a]pyrene

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this