TY - JOUR
T1 - Dynamic fast‐atom bombardment mass spectrometry of conjugated metabolites of benzo[a]pyrene
AU - Yang, Yang
AU - Egestad, Börje
AU - Jernström, Bengt
AU - Sjöovall, Jan
AU - Gustafsson, Jan‐Åke
AU - Rafter, Joseph
AU - Bailli, T. A.
N1 - Copyright:
Copyright 2016 Elsevier B.V., All rights reserved.
PY - 1991/11
Y1 - 1991/11
N2 - The N‐acetylcysteine, cysteine and gluathione conjugates of r‐7,t‐8‐dihydroxy‐t‐9,10‐oxy‐7,8,9,10‐tetrahydrobenzo[a]pyrene as well as sulphuric and glucuronic acid conjugates of hydroxybenzo[a]pyrenes have been studied by fast‐atom bombardment mass spectrometry (FABMS). Dynamic FABMS has been shown to be advantageous over conventional static FABMS giving more intense spectra with less material in both positive‐and negative‐ion modes. The spectra show quasmolecular ions and fragment ions indicative of the aglycome and/or the conjugating group.
AB - The N‐acetylcysteine, cysteine and gluathione conjugates of r‐7,t‐8‐dihydroxy‐t‐9,10‐oxy‐7,8,9,10‐tetrahydrobenzo[a]pyrene as well as sulphuric and glucuronic acid conjugates of hydroxybenzo[a]pyrenes have been studied by fast‐atom bombardment mass spectrometry (FABMS). Dynamic FABMS has been shown to be advantageous over conventional static FABMS giving more intense spectra with less material in both positive‐and negative‐ion modes. The spectra show quasmolecular ions and fragment ions indicative of the aglycome and/or the conjugating group.
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U2 - 10.1002/rcm.1290051103
DO - 10.1002/rcm.1290051103
M3 - Article
AN - SCOPUS:84990655591
SN - 0951-4198
VL - 5
SP - 499
EP - 502
JO - Rapid Communications in Mass Spectrometry
JF - Rapid Communications in Mass Spectrometry
IS - 11
ER -