Dynamic fast‐atom bombardment mass spectrometry of conjugated metabolites of benzo[a]pyrene

Yang Yang, Börje Egestad, Bengt Jernström, Jan Sjöovall, Jan-Ake Gustafsson, Joseph Rafter, T. A. Bailli

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

The N‐acetylcysteine, cysteine and gluathione conjugates of r‐7,t‐8‐dihydroxy‐t‐9,10‐oxy‐7,8,9,10‐tetrahydrobenzo[a]pyrene as well as sulphuric and glucuronic acid conjugates of hydroxybenzo[a]pyrenes have been studied by fast‐atom bombardment mass spectrometry (FABMS). Dynamic FABMS has been shown to be advantageous over conventional static FABMS giving more intense spectra with less material in both positive‐and negative‐ion modes. The spectra show quasmolecular ions and fragment ions indicative of the aglycome and/or the conjugating group.

Original languageEnglish (US)
Pages (from-to)499-502
Number of pages4
JournalRapid Communications in Mass Spectrometry
Volume5
Issue number11
DOIs
StatePublished - 1991

ASJC Scopus subject areas

  • Analytical Chemistry
  • Spectroscopy
  • Organic Chemistry

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