Dual-mode intracranial catheters for minimally-invasive neuro-oncology feasibility study

Carl D. Herickhoff; Edward D. Light; Patrick D. Wolf; Stephen W. Smith; Gerald A. Grant; Gavin W. Britz

doi:10.1109/ULTSYM.2009.5441798

Dual-mode intracranial catheters for minimally-invasive neuro-oncology feasibility study

Carl D. Herickhoff, Edward D. Light, Patrick D. Wolf, Stephen W. Smith, Gerald A. Grant, Gavin W. Britz

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

4 Scopus citations

Abstract

In this study, we investigated the feasibility of dual-mode intracranial catheter transducers for visualization and treatment of tumors in the brain. Feasibility is demonstrated in two ways: 1) by developing a 12 Fr, integrated matrix and linear array catheter transducer prototype for combined real-time 3D imaging and heating, and 2) by testing 3.5 Fr IVUS-catheter-packageable transducers for therapeutic potential. The 3.6 MHz, 12 Fr catheter acquired real-time 3D images of canine brain structures in vivo while placed in the superior sagittal sinus via a burr hole in the skull, and achieved a 3.5°C temperature rise in tissue-mimicking material at a 2 cm focus in vitro. The IVUS-sized prototype transducers were tested for maximum intensity and mechanical index, and a thermal model was used to extrapolate and estimate each transducer's maximum potential temperature rise in brain tissue.

Original language	English (US)
Title of host publication	2009 IEEE International Ultrasonics Symposium and Short Courses, IUS 2009
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	1012-1015
Number of pages	4
ISBN (Print)	9781424443895
DOIs	https://doi.org/10.1109/ULTSYM.2009.5441798
State	Published - 2009
Event	2009 IEEE International Ultrasonics Symposium, IUS 2009 - Rome, Italy Duration: Sep 20 2009 → Sep 23 2009

Publication series

Name	Proceedings - IEEE Ultrasonics Symposium
ISSN (Print)	1051-0117

Other

Other	2009 IEEE International Ultrasonics Symposium, IUS 2009
Country/Territory	Italy
City	Rome
Period	9/20/09 → 9/23/09

Keywords

Dual-mode catheter transducer
Intravascular ultrasound
Ultrasound hyperthermia

ASJC Scopus subject areas

Acoustics and Ultrasonics

Access to Document

10.1109/ULTSYM.2009.5441798

Cite this

Herickhoff, C. D., Light, E. D., Wolf, P. D., Smith, S. W., Grant, G. A., & Britz, G. W. (2009). Dual-mode intracranial catheters for minimally-invasive neuro-oncology feasibility study. In 2009 IEEE International Ultrasonics Symposium and Short Courses, IUS 2009 (pp. 1012-1015). Article 5441798 (Proceedings - IEEE Ultrasonics Symposium). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ULTSYM.2009.5441798

Dual-mode intracranial catheters for minimally-invasive neuro-oncology feasibility study. / Herickhoff, Carl D.; Light, Edward D.; Wolf, Patrick D. et al.
2009 IEEE International Ultrasonics Symposium and Short Courses, IUS 2009. Institute of Electrical and Electronics Engineers Inc., 2009. p. 1012-1015 5441798 (Proceedings - IEEE Ultrasonics Symposium).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Herickhoff, CD, Light, ED, Wolf, PD, Smith, SW, Grant, GA & Britz, GW 2009, Dual-mode intracranial catheters for minimally-invasive neuro-oncology feasibility study. in 2009 IEEE International Ultrasonics Symposium and Short Courses, IUS 2009., 5441798, Proceedings - IEEE Ultrasonics Symposium, Institute of Electrical and Electronics Engineers Inc., pp. 1012-1015, 2009 IEEE International Ultrasonics Symposium, IUS 2009, Rome, Italy, 9/20/09. https://doi.org/10.1109/ULTSYM.2009.5441798

Herickhoff CD, Light ED, Wolf PD, Smith SW, Grant GA, Britz GW. Dual-mode intracranial catheters for minimally-invasive neuro-oncology feasibility study. In 2009 IEEE International Ultrasonics Symposium and Short Courses, IUS 2009. Institute of Electrical and Electronics Engineers Inc. 2009. p. 1012-1015. 5441798. (Proceedings - IEEE Ultrasonics Symposium). doi: 10.1109/ULTSYM.2009.5441798

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abstract = "In this study, we investigated the feasibility of dual-mode intracranial catheter transducers for visualization and treatment of tumors in the brain. Feasibility is demonstrated in two ways: 1) by developing a 12 Fr, integrated matrix and linear array catheter transducer prototype for combined real-time 3D imaging and heating, and 2) by testing 3.5 Fr IVUS-catheter-packageable transducers for therapeutic potential. The 3.6 MHz, 12 Fr catheter acquired real-time 3D images of canine brain structures in vivo while placed in the superior sagittal sinus via a burr hole in the skull, and achieved a 3.5°C temperature rise in tissue-mimicking material at a 2 cm focus in vitro. The IVUS-sized prototype transducers were tested for maximum intensity and mechanical index, and a thermal model was used to extrapolate and estimate each transducer's maximum potential temperature rise in brain tissue.",

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AB - In this study, we investigated the feasibility of dual-mode intracranial catheter transducers for visualization and treatment of tumors in the brain. Feasibility is demonstrated in two ways: 1) by developing a 12 Fr, integrated matrix and linear array catheter transducer prototype for combined real-time 3D imaging and heating, and 2) by testing 3.5 Fr IVUS-catheter-packageable transducers for therapeutic potential. The 3.6 MHz, 12 Fr catheter acquired real-time 3D images of canine brain structures in vivo while placed in the superior sagittal sinus via a burr hole in the skull, and achieved a 3.5°C temperature rise in tissue-mimicking material at a 2 cm focus in vitro. The IVUS-sized prototype transducers were tested for maximum intensity and mechanical index, and a thermal model was used to extrapolate and estimate each transducer's maximum potential temperature rise in brain tissue.

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Dual-mode intracranial catheters for minimally-invasive neuro-oncology feasibility study

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