DrugMap Central: An on-line query and visualization tool to facilitate drug repositioning studies

Changhe Fu, Guangxu Jin, Junfeng Gao, Rui Zhu, Efren Ballesteros-Villagrana, Stephen T.C. Wong

    Research output: Contribution to journalArticlepeer-review

    31 Scopus citations

    Abstract

    Systematic studies of drug repositioning require the integration of multi-level drug data, including basic chemical information (such as SMILES), drug targets, target-related signaling pathways, clinical trial information and Food and Drug Administration (FDA)- approval information, to predict new potential indications of existing drugs. Currently available databases, however, lack query support for multi-level drug information and thus are not designed to support drug repositioning studies. DrugMap Central (DMC), an online tool, is developed to help fill the gap. DMC enables the users to integrate, query, visualize, interrogate, and download multi-level data of known drugs or compounds quickly for drug repositioning studies all within one system.

    Original languageEnglish (US)
    Pages (from-to)1834-1836
    Number of pages3
    JournalBioinformatics
    Volume29
    Issue number14
    DOIs
    StatePublished - Jul 15 2013

    ASJC Scopus subject areas

    • Statistics and Probability
    • Biochemistry
    • Molecular Biology
    • Computer Science Applications
    • Computational Theory and Mathematics
    • Computational Mathematics

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