Drug treatment of hyperlipidemia

D. Yeshurun, A. M. Gotto

Research output: Contribution to journalReview articlepeer-review

40 Scopus citations


The most frequent indication for treatment of hyperlipidemia is for prevention of arteriosclerosis, a suspected but unproved benefit. The cornerstone of treatment of primary hyperlipidemia is diet; drugs may be added to, but do not replace, diet. When a drug is used with any patient, its potential benefits and hazards must be carefully weighed for the given subject. The subjects should be carefully followed and observed for side effects. Plasma lipids should be monitored during the course of treatment. Five drugs have been approved by the U.S. Food and Drug Administration for the treatment of hyperlipidemia: cholestyramine, clofibrate, nicotinic acid, sodium dextrothyroxine and beta-sitosterol. The use, the actions and the side effects of each and of several nonapproved agents are discussed.

Original languageEnglish (US)
Pages (from-to)379-396
Number of pages18
JournalThe American journal of medicine
Issue number3
StatePublished - Mar 1976

ASJC Scopus subject areas

  • Medicine(all)


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