Drug-induced paraparotid fat deposition in patients with HIV: Case reports

Louis Mandel, David Alfi

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Background. The treatment of patients with HIV is managed effectively with highly active antiretroviral therapy, but complications in the form of a lipodystrophy syndrome (LDS) often develop. Case Descriptions. The authors describe two patients who had bilateral parotid area fatty swellings, which are a manifestation of the fat redistribution seen in LDS. Fat hypertrophy, fat atrophy or both in other regions; dyslipidemia; and glucose abnormalities also were present. Conclusion and Clinical Implications. Although the LDS in patients with HIV is recognized visibly by fat redistribution, the syndrome includes dyslipidemia and insulin resistance. Dental visits give dentists the opportunity to recognize HIV-related cervicofacial fat alterations. For appropriate attention, referral to the patient's physician who is managing the HIV is indicated.

Original languageEnglish (US)
Pages (from-to)152-157
Number of pages6
JournalJournal of the American Dental Association
Issue number2
StatePublished - Feb 2008


  • Highly active antiretroviral therapy
  • Lipodystrophy
  • Lipodystrophy syndrome
  • Paraparotid fat

ASJC Scopus subject areas

  • Dentistry(all)


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