TY - JOUR
T1 - Drug-induced paraparotid fat deposition in patients with HIV
T2 - Case reports
AU - Mandel, Louis
AU - Alfi, David
PY - 2008/1/1
Y1 - 2008/1/1
N2 - Background. The treatment of patients with HIV is managed effectively with highly active antiretroviral therapy, but complications in the form of a lipodystrophy syndrome (LDS) often develop. Case Descriptions. The authors describe two patients who had bilateral parotid area fatty swellings, which are a manifestation of the fat redistribution seen in LDS. Fat hypertrophy, fat atrophy or both in other regions; dyslipidemia; and glucose abnormalities also were present. Conclusion and Clinical Implications. Although the LDS in patients with HIV is recognized visibly by fat redistribution, the syndrome includes dyslipidemia and insulin resistance. Dental visits give dentists the opportunity to recognize HIV-related cervicofacial fat alterations. For appropriate attention, referral to the patient's physician who is managing the HIV is indicated.
AB - Background. The treatment of patients with HIV is managed effectively with highly active antiretroviral therapy, but complications in the form of a lipodystrophy syndrome (LDS) often develop. Case Descriptions. The authors describe two patients who had bilateral parotid area fatty swellings, which are a manifestation of the fat redistribution seen in LDS. Fat hypertrophy, fat atrophy or both in other regions; dyslipidemia; and glucose abnormalities also were present. Conclusion and Clinical Implications. Although the LDS in patients with HIV is recognized visibly by fat redistribution, the syndrome includes dyslipidemia and insulin resistance. Dental visits give dentists the opportunity to recognize HIV-related cervicofacial fat alterations. For appropriate attention, referral to the patient's physician who is managing the HIV is indicated.
KW - Highly active antiretroviral therapy
KW - Lipodystrophy
KW - Lipodystrophy syndrome
KW - Paraparotid fat
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U2 - 10.14219/jada.archive.2008.0130
DO - 10.14219/jada.archive.2008.0130
M3 - Article
C2 - 18245682
AN - SCOPUS:39749114434
VL - 139
SP - 152
EP - 157
JO - Journal of the American Dental Association
JF - Journal of the American Dental Association
SN - 0002-8177
IS - 2
ER -