Downregulation of the endothelial histone demethylase JMJD3 is associated with neointimal hyperplasia of arteriovenous fistulas in kidney failure

Medicine and Dentistry

• Downregulation 100%
• Neointimal Hyperplasia 100%
• Renal Failure 100%
• Arteriovenous Fistula 100%
• Synapsin II 100%
• Histone Demethylase 100%
• Endothelial Cell 41%
• Chronic Kidney Disease 16%
• Neointima 16%
• Cell Regeneration 16%
• Promoter Region 8%
• Cell Function 8%
• Nitric Oxide 8%
• Gene Promoter 8%
• Methylation 8%
• Nephropathy 8%
• Endothelial Nitric Oxide Synthase 8%
• Vascularity 8%
• Transcription Factor 8%
• Surgical Anastomosis 8%
• Inflammatory Cell 8%
• Endothelial Dysfunction 8%
• Cell Marker 8%
• Cellular Infiltration 8%
• Evans Blue 8%
• Vascular Smooth Muscle Cell 8%
• Histone H3 8%
• Transforming Growth Factor Beta 8%
• Lysine 8%

Keyphrases

• Intimal Hyperplasia 100%
• Arteriovenous Fistula 100%
• Kidney Failure 100%
• Jumonji 100%
• Histone Demethylase 100%
• Endothelial Cells 33%
• Knockdown 16%
• Chronic Kidney Disease 16%
• Neointima Formation 16%
• H3K27 Acetylation 16%
• Cell Regeneration 16%
• Transforming Growth Factor-β 8%
• Transcriptional Activity 8%
• Gene Promoter 8%
• Decreased Expression 8%
• Nitric Oxide Production 8%
• Endothelial Nitric Oxide Synthase (eNOS) 8%
• Vasculature 8%
• Endothelial Regeneration 8%
• Vascular Smooth muscle Cells 8%
• Transcription Factor 8%
• Endothelial Dysfunction 8%
• Cell Function 8%
• Hes1 8%
• Anastomosis 8%
• Inflammatory Cell Infiltration 8%
• Evans Blue 8%
• Histone H3 Lysine 27 8%
• Endothelial Markers 8%
• Negatively Associated 8%
• Fistula Patency 8%
• Blue Staining 8%
• Endothelial Barrier Function 8%
• Endothelial-to-mesenchymal Transition (EndMT) 8%
• Patients with Kidney Disease 8%