Doppler assessment of right ventricular filling dynamics in systemic hypertension: comparison with left ventricular filling

Gabriel B. Habib, William A. Zoghbi

Research output: Contribution to journalArticle

30 Scopus citations

Abstract

To assess right ventricular filling dynamics in systemic hypertension, pulsed Doppler echocardiographic studies were obtained at the tricuspid and mitral anuli in 43 untreated hypertensive patients, aged 23 to 66 years, and in 42 age-matched normotensive control subjects. In hypertensive patients, the ratio of late to early peak filling velocity and atrial filling fraction were higher, while normalized peak filling rate, one third and one half filling fractions were lower, compared with control values. Right ventricular filling dynamics correlated poorly with age in hypertensive patients, and were unrelated to left ventricular mass or left ventricular wall thickness. Weak correlations were only found between right ventricular wall thickness and right ventricular peak late inflow velocity, first half and first third filling fractions. However, right ventricular filling dynamics were closely related to left ventricular filling dynamics in both hypertensive patients (r = 0.49 to 0.82) and normal individuals (r = 0.55 to 0.86). Thus right ventricular filling dynamics are altered in hypertension, independently of left ventricular mass or blood pressure, are weakly related to right ventricular thickness, but remain closely correlated to left ventricular filling dynamics.

Original languageEnglish (US)
Pages (from-to)1313-1320
Number of pages8
JournalAmerican Heart Journal
Volume124
Issue number5
DOIs
StatePublished - Nov 1992

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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