Does sedation offer better outcomes than local anaesthesia for thyroid FNA in adult patients?

R. M. Kholmatov, H. S. Khadra, F. Murad, T. M. Ahmed, A. B. Sholl, E. Kandil

Research output: Contribution to journalArticlepeer-review


Objective: To examine the potential benefits of sedation in adults undergoing fine needle aspiration (FNA) of thyroid nodules. Methods: This retrospective study compared the outcomes of sedated and non-sedated FNA patients. Results: A total of 860 patients underwent 1698 FNAs of thyroid nodules. The mean patient age was 52.4±14.4 years, and 80.2% of patients were women. The non-sedated group consisted of 782 patients with 1543 (93.5%) FNA procedures. The sedated group consisted of 66 patients who underwent 107 (6.5%) FNAs. There was no statistical difference between these groups with respect to age, gender, nodule size, nodule vascularity, non-diagnostic sample rate and post FNA hematoma (P >.05). Conclusions: Performing FNA of thyroid nodules in adult patients under sedation is not associated with a higher diagnostic yield or lower bleeding rate when compared to local anesthesia. Sedation should be judiciously used on only very anxious patients due to the increased overall cost.

Original languageEnglish (US)
Pages (from-to)201-204
Number of pages4
Issue number2
StatePublished - Apr 2018


  • fine needle aspiration
  • local anaesthesia
  • non-diagnostic sample
  • sedation
  • thyroid nodules

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology


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