Abstract
Novel, potent tumor-associated antigens are needed to improve the efficacy of immunotherapy for myeloma. We demonstrated that active vaccination using the DKK1-DNA vaccine in the myeloma mouse model protected mice from developing myeloma and effectively treated established myeloma. Therefore, DKK1 could be developed as a novel vaccine for myeloma immunotherapy.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 756-758 |
| Number of pages | 3 |
| Journal | OncoImmunology |
| Volume | 1 |
| Issue number | 5 |
| DOIs | |
| State | Published - 2012 |
Keywords
- DNA
- Dickkopf-1
- Immunotherapy
- Multiple myeloma
- Vaccine
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
- Oncology