Abstract

Novel, potent tumor-associated antigens are needed to improve the efficacy of immunotherapy for myeloma. We demonstrated that active vaccination using the DKK1-DNA vaccine in the myeloma mouse model protected mice from developing myeloma and effectively treated established myeloma. Therefore, DKK1 could be developed as a novel vaccine for myeloma immunotherapy.

Original languageEnglish (US)
Pages (from-to)756-758
Number of pages3
JournalOncoImmunology
Volume1
Issue number5
DOIs
StatePublished - 2012

Keywords

  • DNA
  • Dickkopf-1
  • Immunotherapy
  • Multiple myeloma
  • Vaccine

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Oncology

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