Distribution of TiO2 particles in the olfactory bulb of mice after nasal inhalation using microbeam SRXRF mapping techniques

J. X. Wang, C. Y. Chen, H. W. Yu, J. Sun, B. Li, Y. F. Li, Y. X. Gao, W. He, Y. Y. Huang, Z. F. Chai, Y. L. Zhao, X. Y. Deng, H. F. Sun

Research output: Contribution to journalArticle

40 Scopus citations

Abstract

The characterization of different sized TiO2 (25 nm, 80 nm, and 155 nm) was carried out by transmission electron microscopy (TEM) and the micro-distributions of TiO2 in the olfactory bulb of mice after nasal inhalation were investigated by microbeam SRXRF mapping techniques. The results show that TiO2 particles can be translocated to the olfactory bulb through the olfactory nerve system after inhalation. The distributions of Fe, Cu, and Zn in the olfactory bulb were also studied.

Original languageEnglish (US)
Pages (from-to)527-531
Number of pages5
JournalJournal of Radioanalytical and Nuclear Chemistry
Volume272
Issue number3
DOIs
StatePublished - Jun 2007

ASJC Scopus subject areas

  • Analytical Chemistry
  • Nuclear Energy and Engineering
  • Radiology Nuclear Medicine and imaging
  • Pollution
  • Spectroscopy
  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

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