Direct preparation of polyfunctional amino-substituted arylmagnesium reagents via an iodine-magnesium exchange reaction

Greta Varchi; Christiane Kofink; David M. Lindsay; Alfredo Ricci; Paul Knochel

doi:10.1039/b211115b

Direct preparation of polyfunctional amino-substituted arylmagnesium reagents via an iodine-magnesium exchange reaction

Greta Varchi, Christiane Kofink, David M. Lindsay, Alfredo Ricci, Paul Knochel

Houston Methodist

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

The successive addition of PhMgCl and i-PrMgCl to functionalised iodoanilines allows their conversion to the corresponding amino-functionalised Grignard reagents, which react smoothly with a range of electrophiles in high yield.

Original language	English (US)
Pages (from-to)	396-397
Number of pages	2
Journal	Chemical Communications
Volume	3
Issue number	3
DOIs	https://doi.org/10.1039/b211115b
State	Published - 2003

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/b211115b

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@article{45a43a3027b8465bbb6833e00ed52e6f,

title = "Direct preparation of polyfunctional amino-substituted arylmagnesium reagents via an iodine-magnesium exchange reaction",

abstract = "The successive addition of PhMgCl and i-PrMgCl to functionalised iodoanilines allows their conversion to the corresponding amino-functionalised Grignard reagents, which react smoothly with a range of electrophiles in high yield.",

author = "Greta Varchi and Christiane Kofink and Lindsay, \{David M.\} and Alfredo Ricci and Paul Knochel",

year = "2003",

doi = "10.1039/b211115b",

language = "English (US)",

volume = "3",

pages = "396--397",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "3",

}

TY - JOUR

T1 - Direct preparation of polyfunctional amino-substituted arylmagnesium reagents via an iodine-magnesium exchange reaction

AU - Varchi, Greta

AU - Kofink, Christiane

AU - Lindsay, David M.

AU - Ricci, Alfredo

AU - Knochel, Paul

PY - 2003

Y1 - 2003

N2 - The successive addition of PhMgCl and i-PrMgCl to functionalised iodoanilines allows their conversion to the corresponding amino-functionalised Grignard reagents, which react smoothly with a range of electrophiles in high yield.

AB - The successive addition of PhMgCl and i-PrMgCl to functionalised iodoanilines allows their conversion to the corresponding amino-functionalised Grignard reagents, which react smoothly with a range of electrophiles in high yield.

UR - https://www.scopus.com/pages/publications/0037423429

UR - https://www.scopus.com/inward/citedby.url?scp=0037423429&partnerID=8YFLogxK

U2 - 10.1039/b211115b

DO - 10.1039/b211115b

M3 - Article

C2 - 12613630

AN - SCOPUS:0037423429

SN - 1359-7345

VL - 3

SP - 396

EP - 397

JO - Chemical Communications

JF - Chemical Communications

IS - 3

ER -

Direct preparation of polyfunctional amino-substituted arylmagnesium reagents via an iodine-magnesium exchange reaction

Abstract

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