Abstract
Diffusion tensor imaging (DTI) is an effective modality in studying the connectivity of the brain. To eliminate possible biases caused by fiber extraction approaches due to low spatial resolution of DTI and the number of fibers obtained, the fast marching (FM) algorithm based on the whole diffusion tensor information is proposed to model and study the brain connectivity network. Our observation is that the connectivity extracted from the whole tensor field would be more robust and reliable for constructing brain connectivity network using DTI data. To construct the connectivity network, in this paper, the arrival time map and the velocity map generated by the FM algorithm are combined to define the connectivity strength among different brain regions. The conventional fiber tracking-based and the proposed tensor-based FM connectivity methods are compared, and the results indicate that the connectivity features obtained using the FM-based method agree better with the neuromorphical studies of the human brain.
Original language | English (US) |
---|---|
Pages (from-to) | 167-178 |
Number of pages | 12 |
Journal | Computerized Medical Imaging and Graphics |
Volume | 35 |
Issue number | 3 |
DOIs | |
State | Published - Apr 2011 |
Keywords
- Brain connectivity analysis
- Diffusion tensor imaging
- Fast marching
- Fiber tracking
- Tractography
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Health Informatics
- Radiological and Ultrasound Technology
- Computer Graphics and Computer-Aided Design
- Computer Vision and Pattern Recognition