Differential gene expression in response to methoxychlor and estradiol through ERα, ERβ, and AR in reproductive tissues of female mice

Medicine & Life Sciences

• 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane 100%
• Methoxychlor 81%
• Androgen Receptors 51%
• Estrogen Receptors 45%
• Estradiol 42%
• Gene Expression 28%
• Flutamide 20%
• Uterus 17%
• Ovary 12%
• Cathepsin B 12%
• Genes 9%
• Insulin-Like Growth Factor Binding Protein 5 7%
• Overlapping Genes 7%
• Estrogen Receptor Antagonists 6%
• Ligands 6%
• Clusterin 6%
• Androgen Antagonists 6%
• Mixed Function Oxygenases 5%
• Somatomedins 5%
• Glutathione Transferase 5%
• Progesterone Receptors 5%
• Glutathione Peroxidase 5%
• Oligonucleotide Array Sequence Analysis 5%
• Cytochrome P-450 Enzyme System 4%
• Rodentia 4%
• RNA 3%
• Pathology 3%
• Polymerase Chain Reaction 2%
• Messenger RNA 2%

Chemistry

• Methoxychlor 78%
• Androgen 60%
• Estradiol 56%
• Estrogen 51%
• Flutamide 33%
• Reproductive Effect 12%
• Glutathione 12%
• Antiandrogen 10%
• Developmental 8%
• Microarrays 7%
• Cytochrome P450 7%
• Complementary DNA 7%
• Agonist 6%
• Antagonist 6%
• Peroxidase 6%
• Metabolite 4%
• Ligand 3%
• Protein 2%