Diastereoselective synthesis of diamino 1,2-diols from homochiral α-aminoacylsilanes

B. F. Bonini, M. Comes-Franchini, M. Fochi, L. Lunazzi, A. Mazzanti, G. Mazzanti, A. Ricci, G. Varchi

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


We have developed a new synthetic access to stereodefined diamino 1,2-diols starting from homochiral α-aminoacylsilanes. A [3+2] cycloaddition with benzo nitrile oxide of the vinylated adducts and a reductive ring opening constitute key steps of the reaction sequence.

Original languageEnglish (US)
Pages (from-to)995-998
Number of pages4
Issue numberSPEC. ISS
StatePublished - 2001


  • Aminopolyols
  • Dipolar cycloaddition
  • Vinylation
  • α-aminoacylsilanes

ASJC Scopus subject areas

  • Organic Chemistry


Dive into the research topics of 'Diastereoselective synthesis of diamino 1,2-diols from homochiral α-aminoacylsilanes'. Together they form a unique fingerprint.

Cite this