Diagnostic delay of pulmonary nontuberculous mycobacterial infection in China

Hui Jing; Wanming Tan; Yunfeng Deng; Dachuan Gao; Liang Li; Zhiming Lu; Edward A. Graviss; Xin Ma

doi:10.1186/2049-6958-9-48

Diagnostic delay of pulmonary nontuberculous mycobacterial infection in China

Hui Jing, Wanming Tan, Yunfeng Deng, Dachuan Gao, Liang Li, Zhiming Lu, Edward A. Graviss, Xin Ma

Research output: Contribution to journal › Article

6 Scopus citations

Abstract

Background: Nontuberculous mycobacteria (NTM) infection is an emerging, but neglected public health concern in China. Findings: To investigate diagnostic delay of NTM diseases in China, we analyzed 91 patients with pulmonary NTM infection in Shandong Province. The median diagnostic delay time of the analyzed patients was 84 days, which was significantly associated with rural inhabitance (135 days vs. 73 days of urban inhabitance, p <0.01) and lower level of first visiting hospitals/clinics (70 and 82 days of tertiary and secondary hospitals/clinics respectively vs. 120 days of primary hospitals/clinics, p <0.05). M. farcinogenes was isolated from a 79-year-old male patient, which is the first report of pulmonary infection in humans. Conclusions: Our results indicate a significant diagnostic delay of NTM diseases in China, especially for rural patients with limited access to higher-level healthcare services.

Original language	English (US)
Article number	48
Pages (from-to)	48
Journal	Multidisciplinary Respiratory Medicine
Volume	9
Issue number	1
DOIs	https://doi.org/10.1186/2049-6958-9-48
State	Published - Sep 11 2014

Keywords

China
Infection
Nontuberculous mycobacterium

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine

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title = "Diagnostic delay of pulmonary nontuberculous mycobacterial infection in China",

abstract = "Background: Nontuberculous mycobacteria (NTM) infection is an emerging, but neglected public health concern in China. Findings: To investigate diagnostic delay of NTM diseases in China, we analyzed 91 patients with pulmonary NTM infection in Shandong Province. The median diagnostic delay time of the analyzed patients was 84 days, which was significantly associated with rural inhabitance (135 days vs. 73 days of urban inhabitance, p <0.01) and lower level of first visiting hospitals/clinics (70 and 82 days of tertiary and secondary hospitals/clinics respectively vs. 120 days of primary hospitals/clinics, p <0.05). M. farcinogenes was isolated from a 79-year-old male patient, which is the first report of pulmonary infection in humans. Conclusions: Our results indicate a significant diagnostic delay of NTM diseases in China, especially for rural patients with limited access to higher-level healthcare services.",

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AU - Jing, Hui

AU - Tan, Wanming

AU - Deng, Yunfeng

AU - Gao, Dachuan

AU - Li, Liang

AU - Lu, Zhiming

AU - Graviss, Edward A.

AU - Ma, Xin

PY - 2014/9/11

Y1 - 2014/9/11

N2 - Background: Nontuberculous mycobacteria (NTM) infection is an emerging, but neglected public health concern in China. Findings: To investigate diagnostic delay of NTM diseases in China, we analyzed 91 patients with pulmonary NTM infection in Shandong Province. The median diagnostic delay time of the analyzed patients was 84 days, which was significantly associated with rural inhabitance (135 days vs. 73 days of urban inhabitance, p <0.01) and lower level of first visiting hospitals/clinics (70 and 82 days of tertiary and secondary hospitals/clinics respectively vs. 120 days of primary hospitals/clinics, p <0.05). M. farcinogenes was isolated from a 79-year-old male patient, which is the first report of pulmonary infection in humans. Conclusions: Our results indicate a significant diagnostic delay of NTM diseases in China, especially for rural patients with limited access to higher-level healthcare services.

AB - Background: Nontuberculous mycobacteria (NTM) infection is an emerging, but neglected public health concern in China. Findings: To investigate diagnostic delay of NTM diseases in China, we analyzed 91 patients with pulmonary NTM infection in Shandong Province. The median diagnostic delay time of the analyzed patients was 84 days, which was significantly associated with rural inhabitance (135 days vs. 73 days of urban inhabitance, p <0.01) and lower level of first visiting hospitals/clinics (70 and 82 days of tertiary and secondary hospitals/clinics respectively vs. 120 days of primary hospitals/clinics, p <0.05). M. farcinogenes was isolated from a 79-year-old male patient, which is the first report of pulmonary infection in humans. Conclusions: Our results indicate a significant diagnostic delay of NTM diseases in China, especially for rural patients with limited access to higher-level healthcare services.

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