Diagnosis and treatment of liver abscess after orthotopic liver transplantation

Gen shu Wang, Gui hua Chen, Xiao shun He, Xiao feng Zhu, Min qiang Lu, Yang Yang, Chang jie Cai, Guo dong Wang

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

OBJECTIVE: To investigate etiology, diagnosis, treatment and prophylaxis of liver abscess after orthotopic liver transplantation (OLT). METHODS: Of 274 recipients of OLT from January 1993 to June 2003 in our transplant center, liver abscess were identified in 6 recipients (2.2%). The clinical presentation included fever, shiver, abdominal pain, jaundice, hepatic dysfunction, hypoalbuminemia, anemia, leukocytosis and neutrophilia. They were diagnosed mainly according to the clinical presentation and Ultrasonography or CT scan. The treatments included aspiration and drainage of abscess, removing bile sludge, antibiotics and supportive therapy. RESULTS: Of 6 patients, 2 were cured, 3 refused liver retransplantation and 2 died of serious systemic infection. The cure rate was 33.3%. CONCLUSIONS: the etiology of liver abscess after OLT is complicated. The predisposing factors might be included hepatic artery thrombosis or stenosis, MP pulse therapy, cholangitis and biliary interventional therapy. Its prognosis seemed disappointing. Strong prophylactic measures should be recommended to reduce the liver abscess after OLT.

Original languageEnglish (US)
Pages (from-to)335-336
Number of pages2
JournalZhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology
Volume12
Issue number6
StatePublished - Jun 2004

ASJC Scopus subject areas

  • Medicine(all)

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