TY - JOUR
T1 - Development of clear cell adenocarcinoma in des-exposed offspring under observation
AU - Kaufman, Raymond H.
AU - Korhonen, Matti O.
AU - Strama, Thomas
AU - Adam, Ervin
AU - Kaplan, Alan L.
PY - 1982/1/1
Y1 - 1982/1/1
N2 - Two cases of clear cell adenocarcinoma of the vagina detected at follow-up in young women exposed in utero to diethylstilbestrol are reported. One patient, aged 23, had been followed for 2 years before carcinoma was diagnosed; the second patient, aged 22, had been seen on a regular basis for 5 years, 8 months. In both instances, suspicion of the presence of carcinoma was aroused by the palpation of a small nodule in the vaginal fornix. Hysterosalpinography was performed on both patients and, in 1 instance, an abnormal x-ray film was reflected by the gross appearance of the uterine cavity found in the surgical specimen.
AB - Two cases of clear cell adenocarcinoma of the vagina detected at follow-up in young women exposed in utero to diethylstilbestrol are reported. One patient, aged 23, had been followed for 2 years before carcinoma was diagnosed; the second patient, aged 22, had been seen on a regular basis for 5 years, 8 months. In both instances, suspicion of the presence of carcinoma was aroused by the palpation of a small nodule in the vaginal fornix. Hysterosalpinography was performed on both patients and, in 1 instance, an abnormal x-ray film was reflected by the gross appearance of the uterine cavity found in the surgical specimen.
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M3 - Article
C2 - 7088431
AN - SCOPUS:0020070961
SN - 0029-7844
VL - 59
SP - 68S-72S
JO - Obstetrics and Gynecology
JF - Obstetrics and Gynecology
IS - 6
ER -