Determination of regurgitant fraction in isolated mitral or aortic regurgitation by pulsed Doppler two-dimensional echocardiography

Roxann Rokey, Leroy L. Sterling, William A. Zoghbi, Michele P. Sartori, Marian C. Limacher, Lawrence C. Kuo, Miguel A. Quiñones

Research output: Contribution to journalArticle

211 Scopus citations

Abstract

Measurements of mitral and aortic valve flows were obtained with two-dimensional Doppler echocardiography in 25 patients with isolated mitral (n = 19) or aortic (n = 6) regurgitation and regurgitant fraction was calculated as the difference between the two flows divided by the flow through the regurgitant valve. Results were compared with measurements of regurgitant fraction determined by combined left ventricular angiography and thermodilution. Regurgitant fraction averaged 56 ± 18% (range 19 to 79) by Doppler echocardiography and 48 ± 17% (range 13 to 72) by angiography. A significant correlation was observed between the two methods (r = 0.91;SEE = 7%). In contrast, no significant correlation was found between regurgitant fraction measured by either method and the angiographic 1+ to 4+ qualitative classification of regurgitation. Doppler echocardiography appears to be an accurate method for the non-invasive quantification of severity of regurgitation in isolated left-sided valve lesions.

Original languageEnglish (US)
Pages (from-to)1273-1278
Number of pages6
JournalJournal of the American College of Cardiology
Volume7
Issue number6
DOIs
StatePublished - 1986

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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