This paper reports the development and application of an analytical method in which both polyethylene glycol ethers or polyethylene glycols are converted into ethylene dibromide via treatment with concentrated hydrobromic acid/glacial acetic acid (1:1) at 150°C for 3 hours. This method can detect < 1ppm of the surfactant in biological tissues, however, the practical utility of the technique is dependent on the solvent and reagent purities and the various cleanup methods which include base hydrolysis, high pressure liquid chromatography and Florisil or acidified Florisil column chromatography.
ASJC Scopus subject areas
- Environmental Chemistry
- Health, Toxicology and Mutagenesis