Detection or Trace Levels of Polyethylene Glycol Ether Surfactants in Biological Tissues

D. Fung; S. Safe; J. F.S. Crocker

doi:10.1080/02772248409357045

Detection or Trace Levels of Polyethylene Glycol Ether Surfactants in Biological Tissues

D. Fung, S. Safe, J. F.S. Crocker

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

This paper reports the development and application of an analytical method in which both polyethylene glycol ethers or polyethylene glycols are converted into ethylene dibromide via treatment with concentrated hydrobromic acid/glacial acetic acid (1:1) at 150°C for 3 hours. This method can detect < 1ppm of the surfactant in biological tissues, however, the practical utility of the technique is dependent on the solvent and reagent purities and the various cleanup methods which include base hydrolysis, high pressure liquid chromatography and Florisil or acidified Florisil column chromatography.

Original language	English (US)
Pages (from-to)	109-118
Number of pages	10
Journal	Toxicological & Environmental Chemistry
Volume	8
Issue number	2-3
DOIs	https://doi.org/10.1080/02772248409357045
State	Published - Jun 1 1984

ASJC Scopus subject areas

Environmental Chemistry
Pollution
Health, Toxicology and Mutagenesis

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10.1080/02772248409357045

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title = "Detection or Trace Levels of Polyethylene Glycol Ether Surfactants in Biological Tissues",

abstract = "This paper reports the development and application of an analytical method in which both polyethylene glycol ethers or polyethylene glycols are converted into ethylene dibromide via treatment with concentrated hydrobromic acid/glacial acetic acid (1:1) at 150°C for 3 hours. This method can detect < 1ppm of the surfactant in biological tissues, however, the practical utility of the technique is dependent on the solvent and reagent purities and the various cleanup methods which include base hydrolysis, high pressure liquid chromatography and Florisil or acidified Florisil column chromatography.",

author = "D. Fung and S. Safe and Crocker, {J. F.S.}",

note = "Funding Information: The financial assistance of the Natural Canada is gratefully acknowledged.",

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AU - Fung, D.

AU - Safe, S.

AU - Crocker, J. F.S.

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N2 - This paper reports the development and application of an analytical method in which both polyethylene glycol ethers or polyethylene glycols are converted into ethylene dibromide via treatment with concentrated hydrobromic acid/glacial acetic acid (1:1) at 150°C for 3 hours. This method can detect < 1ppm of the surfactant in biological tissues, however, the practical utility of the technique is dependent on the solvent and reagent purities and the various cleanup methods which include base hydrolysis, high pressure liquid chromatography and Florisil or acidified Florisil column chromatography.

AB - This paper reports the development and application of an analytical method in which both polyethylene glycol ethers or polyethylene glycols are converted into ethylene dibromide via treatment with concentrated hydrobromic acid/glacial acetic acid (1:1) at 150°C for 3 hours. This method can detect < 1ppm of the surfactant in biological tissues, however, the practical utility of the technique is dependent on the solvent and reagent purities and the various cleanup methods which include base hydrolysis, high pressure liquid chromatography and Florisil or acidified Florisil column chromatography.

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Detection or Trace Levels of Polyethylene Glycol Ether Surfactants in Biological Tissues

Abstract

ASJC Scopus subject areas

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