TY - JOUR
T1 - Detection of papillary muscle infarction by late gadolinium enhancement
T2 - Incremental value of short-inversion time vs. standard imaging
AU - Aldrovandi, Annachiara
AU - De Ridder, Stijn P.J.
AU - Strohm, Oliver
AU - Cocker, Myra
AU - Sandonato, Rosa
AU - Friedrich, Matthias G.
N1 - Copyright:
Copyright 2013 Elsevier B.V., All rights reserved.
PY - 2013/5
Y1 - 2013/5
N2 - AimsLate gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) imaging can detect myocardial scar in patients with myocardial infarction. The detection of papillary muscle infarction (PMI) may be difficult due to the bright blood signal. The aim of our study was to evaluate the incremental value of LGE CMR imaging using an inversion recovery (IR)-GRE with a short-inversion time (TI) over standard LGE imaging in identifying PMI.Methods and resultsFifty-six patients with myocardial infarction were studied using a standard IR-GRE LGE sequence with an adjusted TI to null the signal intensity of normal myocardium and with a 3D IR-GRE with a short TI (<180 ms). Signal-to-noise and contrast-to-noise ratios (CNR) and the frequency of PMI were determined. Image quality and infarction sharpness were evaluated. The short-TI LGE sequence detected a higher number of PMI compared with standard LGE sequence (19/54 vs. 15/54) with an increased sharpness of PMI (84.2 vs. 53.3%). The CNR was higher between infarcted myocardium and blood (77.9 ± 60 vs. 19.3 ± 16, P < 0.001) and between PMI and blood (69.4 ± 51 vs. 39.4 ± 26, respectively, P = 0.0157).ConclusionsOur data indicate that in patients with myocardial infarction, LGE CMR imaging using a short TI may be more sensitive than standard LGE imaging for the detection of PMI.
AB - AimsLate gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) imaging can detect myocardial scar in patients with myocardial infarction. The detection of papillary muscle infarction (PMI) may be difficult due to the bright blood signal. The aim of our study was to evaluate the incremental value of LGE CMR imaging using an inversion recovery (IR)-GRE with a short-inversion time (TI) over standard LGE imaging in identifying PMI.Methods and resultsFifty-six patients with myocardial infarction were studied using a standard IR-GRE LGE sequence with an adjusted TI to null the signal intensity of normal myocardium and with a 3D IR-GRE with a short TI (<180 ms). Signal-to-noise and contrast-to-noise ratios (CNR) and the frequency of PMI were determined. Image quality and infarction sharpness were evaluated. The short-TI LGE sequence detected a higher number of PMI compared with standard LGE sequence (19/54 vs. 15/54) with an increased sharpness of PMI (84.2 vs. 53.3%). The CNR was higher between infarcted myocardium and blood (77.9 ± 60 vs. 19.3 ± 16, P < 0.001) and between PMI and blood (69.4 ± 51 vs. 39.4 ± 26, respectively, P = 0.0157).ConclusionsOur data indicate that in patients with myocardial infarction, LGE CMR imaging using a short TI may be more sensitive than standard LGE imaging for the detection of PMI.
KW - Late gadolinium-enhanced cardiovascular magnetic resonance imaging
KW - Myocardial infarction
KW - Papillary muscle infarction
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U2 - 10.1093/ehjci/jes210
DO - 10.1093/ehjci/jes210
M3 - Article
C2 - 23082008
AN - SCOPUS:84876592802
SN - 2047-2404
VL - 14
SP - 495
EP - 499
JO - European Heart Journal Cardiovascular Imaging
JF - European Heart Journal Cardiovascular Imaging
IS - 5
ER -