Detection of human papillomavirus DNA in advanced epithelial ovarian carcinoma

Raymond H. Kaufman; Jacob Bornstein; Alan N. Gordon; Ervin Adam; Alan L. Kaplan; Karen Adler-Storthz

doi:10.1016/0090-8258(87)90256-3

Detection of human papillomavirus DNA in advanced epithelial ovarian carcinoma

Raymond H. Kaufman, Jacob Bornstein, Alan N. Gordon, Ervin Adam, Alan L. Kaplan, Karen Adler-Storthz

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34 Scopus citations

Abstract

Tissue specimens from 10 out of 12 patients with advanced epithelial ovarian adenocarcinoma contained DNA of human papillomavirus type 6 (HPV-6). HPV DNA was identified by in situ hybridization at high stringency using biotin-labeled DNA probes. Nonneoplastic tissue specimens from other pelvic sites of the same patients were also examined. None showed evidence of HPV DNA. The meaning of these findings in relation to epithelial ovarian carcinoma is discussed.

Original language	English (US)
Pages (from-to)	340-349
Number of pages	10
Journal	Gynecologic oncology
Volume	27
Issue number	3
DOIs	https://doi.org/10.1016/0090-8258(87)90256-3
State	Published - Jul 1987

ASJC Scopus subject areas

Oncology
Obstetrics and Gynecology

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10.1016/0090-8258(87)90256-3

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title = "Detection of human papillomavirus DNA in advanced epithelial ovarian carcinoma",

abstract = "Tissue specimens from 10 out of 12 patients with advanced epithelial ovarian adenocarcinoma contained DNA of human papillomavirus type 6 (HPV-6). HPV DNA was identified by in situ hybridization at high stringency using biotin-labeled DNA probes. Nonneoplastic tissue specimens from other pelvic sites of the same patients were also examined. None showed evidence of HPV DNA. The meaning of these findings in relation to epithelial ovarian carcinoma is discussed.",

author = "Kaufman, {Raymond H.} and Jacob Bornstein and Gordon, {Alan N.} and Ervin Adam and Kaplan, {Alan L.} and Karen Adler-Storthz",

note = "Funding Information: {\textquoteright} This work was supported in part by Grant ROI DE 07008 from the National Institutes of Health.",

year = "1987",

month = jul,

doi = "10.1016/0090-8258(87)90256-3",

language = "English (US)",

volume = "27",

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T1 - Detection of human papillomavirus DNA in advanced epithelial ovarian carcinoma

AU - Kaufman, Raymond H.

AU - Bornstein, Jacob

AU - Gordon, Alan N.

AU - Adam, Ervin

AU - Kaplan, Alan L.

AU - Adler-Storthz, Karen

N1 - Funding Information: ’ This work was supported in part by Grant ROI DE 07008 from the National Institutes of Health.

PY - 1987/7

Y1 - 1987/7

N2 - Tissue specimens from 10 out of 12 patients with advanced epithelial ovarian adenocarcinoma contained DNA of human papillomavirus type 6 (HPV-6). HPV DNA was identified by in situ hybridization at high stringency using biotin-labeled DNA probes. Nonneoplastic tissue specimens from other pelvic sites of the same patients were also examined. None showed evidence of HPV DNA. The meaning of these findings in relation to epithelial ovarian carcinoma is discussed.

AB - Tissue specimens from 10 out of 12 patients with advanced epithelial ovarian adenocarcinoma contained DNA of human papillomavirus type 6 (HPV-6). HPV DNA was identified by in situ hybridization at high stringency using biotin-labeled DNA probes. Nonneoplastic tissue specimens from other pelvic sites of the same patients were also examined. None showed evidence of HPV DNA. The meaning of these findings in relation to epithelial ovarian carcinoma is discussed.

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Detection of human papillomavirus DNA in advanced epithelial ovarian carcinoma

Abstract

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