Detection of human papillomavirus DNA in advanced epithelial ovarian carcinoma

Raymond H. Kaufman, Jacob Bornstein, Alan N. Gordon, Ervin Adam, Alan L. Kaplan, Karen Adler-Storthz

Research output: Contribution to journalArticle

30 Scopus citations

Abstract

Tissue specimens from 10 out of 12 patients with advanced epithelial ovarian adenocarcinoma contained DNA of human papillomavirus type 6 (HPV-6). HPV DNA was identified by in situ hybridization at high stringency using biotin-labeled DNA probes. Nonneoplastic tissue specimens from other pelvic sites of the same patients were also examined. None showed evidence of HPV DNA. The meaning of these findings in relation to epithelial ovarian carcinoma is discussed.

Original languageEnglish (US)
Pages (from-to)340-349
Number of pages10
JournalGynecologic oncology
Volume27
Issue number3
DOIs
StatePublished - Jul 1987

ASJC Scopus subject areas

  • Oncology
  • Obstetrics and Gynecology

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