Desmoplastic trichoepithelioma

Adam J. Mamelak, Leonard H. Goldberg, Tracy M. Katz, Jeffery J. Graves, Ofer Arnon, Arash Kimyai-Asadi

Research output: Contribution to journalArticlepeer-review

32 Scopus citations


Background: Desmoplastic trichoepithelioma (DTE) is an uncommon adnexal tumor usually found on the face of young women. Objective: We sought to describe the clinical and histologic characteristics of DTE and discuss management strategies for these tumors. Methods: We conducted a retrospective case series and review of the literature. Results: A series of 17 cases of DTE is reported. Of our patients, 82% were female and half of all these cases occurred on the cheek. Unlike previous reports, the patients in our study were slightly older, with 53% older than 51 years and 71% between the ages of 31 and 60 years at the time of surgery (mean age 49 years, median age 52 years, range 14-81 years). Approximately 38% of the tumors had been present for 1 to 2 years before presentation. The average size of the tumors at the time of surgery was 0.8 × 0.6 cm. All cases were treated with Mohs micrographic surgery. To date, none of the tumors have recurred. Limitations: This is a small case series. The referral patterns of our predominantly Mohs micrographic surgery clinic might further bias this study. Conclusion: DTE is a benign tumor that has a predilection for the face. With its rapid growth, aggressive histologic features that may be confused with basal cell carcinoma, and tendency to arise in cosmetically and functionally sensitive areas, these tumors should be removed in a manner that assures clear surgical margins, such as Mohs micrographic surgery.

Original languageEnglish (US)
Pages (from-to)102-106
Number of pages5
JournalJournal of the American Academy of Dermatology
Issue number1
StatePublished - Jan 2010


  • adnexal neoplasm
  • basal cell carcinoma
  • cutaneous tumors
  • Mohs micrographic surgery
  • skin cancer

ASJC Scopus subject areas

  • Dermatology


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