Designing nanomedicine to overcome therapeutic challenges in pregnancy

Tamar Gross Lev; Assaf Zinger

doi:10.1038/s44222-025-00390-7

Designing nanomedicine to overcome therapeutic challenges in pregnancy

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

Illness during pregnancy presents a therapeutic dilemma: treatment must protect the mother without compromising fetal health. Yet, most drugs remain insufficiently studied in pregnancy. Understanding pregnancy stage-specific drug pharmacokinetics and placental drug transport can guide the design of nanomedicine to optimize treatments during pregnancy.

Original language	English (US)
Pages (from-to)	6-8
Number of pages	3
Journal	Nature Reviews Bioengineering
Volume	4
Issue number	1
Early online date	Dec 2 2025
DOIs	https://doi.org/10.1038/s44222-025-00390-7
State	Published - Jan 2026

ASJC Scopus subject areas

Biophysics
Biomedical Engineering
Applied Microbiology and Biotechnology

Access to Document

10.1038/s44222-025-00390-7

Cite this

@article{8adcf6abe4c946af85eb589c736d11e7,

title = "Designing nanomedicine to overcome therapeutic challenges in pregnancy",

abstract = "Illness during pregnancy presents a therapeutic dilemma: treatment must protect the mother without compromising fetal health. Yet, most drugs remain insufficiently studied in pregnancy. Understanding pregnancy stage-specific drug pharmacokinetics and placental drug transport can guide the design of nanomedicine to optimize treatments during pregnancy.",

author = "\{Gross Lev\}, Tamar and Assaf Zinger",

note = "Publisher Copyright: {\textcopyright} Springer Nature Limited 2025.",

year = "2026",

month = jan,

doi = "10.1038/s44222-025-00390-7",

language = "English (US)",

volume = "4",

pages = "6--8",

journal = "Nature Reviews Bioengineering",

issn = "2731-6092",

publisher = "Springer Nature",

number = "1",

}

TY - JOUR

T1 - Designing nanomedicine to overcome therapeutic challenges in pregnancy

AU - Gross Lev, Tamar

AU - Zinger, Assaf

N1 - Publisher Copyright: © Springer Nature Limited 2025.

PY - 2026/1

Y1 - 2026/1

N2 - Illness during pregnancy presents a therapeutic dilemma: treatment must protect the mother without compromising fetal health. Yet, most drugs remain insufficiently studied in pregnancy. Understanding pregnancy stage-specific drug pharmacokinetics and placental drug transport can guide the design of nanomedicine to optimize treatments during pregnancy.

AB - Illness during pregnancy presents a therapeutic dilemma: treatment must protect the mother without compromising fetal health. Yet, most drugs remain insufficiently studied in pregnancy. Understanding pregnancy stage-specific drug pharmacokinetics and placental drug transport can guide the design of nanomedicine to optimize treatments during pregnancy.

UR - https://www.scopus.com/pages/publications/105023852720

UR - https://www.scopus.com/inward/citedby.url?scp=105023852720&partnerID=8YFLogxK

U2 - 10.1038/s44222-025-00390-7

DO - 10.1038/s44222-025-00390-7

M3 - Comment/debate

AN - SCOPUS:105023852720

SN - 2731-6092

VL - 4

SP - 6

EP - 8

JO - Nature Reviews Bioengineering

JF - Nature Reviews Bioengineering

IS - 1

ER -

Designing nanomedicine to overcome therapeutic challenges in pregnancy

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this