Designing, fabricating, and imaging Raman hot spots

Lidong Qin, Shengli Zou, Can Xue, Ariel Atkinson, George C. Schatz, Chad A. Mirkin

Research output: Contribution to journalArticlepeer-review

401 Scopus citations


We have developed a probe of the electromagnetic mechanism of surface-enhanced Raman scattering via Au nanodisk arrays generated by using on-wire lithography. In this approach, disk thickness and interparticle gap are precisely controlled from 5 nm to many micrometers. Confocal Raman microscopy demonstrates that disk thickness and gap play a crucial role in determining surface-enhanced Raman scattering intensities. Theoretical calculations also demonstrate that these results are consistent with the electromagnetic mechanism, including the surprising result that the largest enhancement does not occur for the smallest gaps.

Original languageEnglish (US)
Pages (from-to)13300-13303
Number of pages4
JournalProceedings of the National Academy of Sciences of the United States of America
Issue number36
StatePublished - Sep 5 2006


  • Discrete dipole approximation
  • Electromagnetic mechanism
  • Nanofabrication
  • Surface-enhanced Raman scattering
  • Templated synthesis

ASJC Scopus subject areas

  • Genetics
  • General


Dive into the research topics of 'Designing, fabricating, and imaging Raman hot spots'. Together they form a unique fingerprint.

Cite this