TY - JOUR
T1 - Design and application of a new rat-specific vacuum erectile device for penile rehabilitation research
AU - Yuan, Jiuhong
AU - Westney, O. Lenaine
AU - Wang, Run
N1 - Funding Information:
The authors would like to acknowledge the Augusta Medical System for unrestricted grant support and Ms Dorothy Stadinger for her editorial assistance.
PY - 2009/12
Y1 - 2009/12
N2 - Introduction.: Radical prostatectomy has a potential negative impact on penile health. The vacuum erection device (VED) has been used to promote the recovery of penile function and to maintain penile length. However, there is skepticism in the urological community due to its elusive mechanisms in penile rehabilitation. Aim.: To design a rat-specific VED and assess its application and safety. Methods.: Based on rat penile measurement and the principle of human VED, the rat-specific VED was designed, and the application for rats was evaluated. Main Outcome Measures.: The vacuum pressure of the rat-specific VED was measured. The VED application on rat penis and its side effects were studied. Results.: The rat-specific VED is a safe and applicable device to study the mechanism of VED in penile rehabilitation. Conclusions.: The newly designed rat-specific VED is a good simulator of the human VED. The application of this device on bilateral cavernous nerve crush rat model will be used to study the mechanisms of the VED in the penile rehabilitation.
AB - Introduction.: Radical prostatectomy has a potential negative impact on penile health. The vacuum erection device (VED) has been used to promote the recovery of penile function and to maintain penile length. However, there is skepticism in the urological community due to its elusive mechanisms in penile rehabilitation. Aim.: To design a rat-specific VED and assess its application and safety. Methods.: Based on rat penile measurement and the principle of human VED, the rat-specific VED was designed, and the application for rats was evaluated. Main Outcome Measures.: The vacuum pressure of the rat-specific VED was measured. The VED application on rat penis and its side effects were studied. Results.: The rat-specific VED is a safe and applicable device to study the mechanism of VED in penile rehabilitation. Conclusions.: The newly designed rat-specific VED is a good simulator of the human VED. The application of this device on bilateral cavernous nerve crush rat model will be used to study the mechanisms of the VED in the penile rehabilitation.
KW - Penile Rehabilitation
KW - Radical Prostatectomy
KW - Rat Specific Vacuum Erectile Device
KW - Vacuum Pressure
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U2 - 10.1111/j.1743-6109.2009.01500.x
DO - 10.1111/j.1743-6109.2009.01500.x
M3 - Article
C2 - 19758281
AN - SCOPUS:77950900092
SN - 1743-6095
VL - 6
SP - 3247
EP - 3253
JO - Journal of Sexual Medicine
JF - Journal of Sexual Medicine
IS - 12
ER -