Deficiency in Repair of the Mitochondrial Genome Sensitizes Proliferating Myoblasts to Oxidative Damage

Keyphrases

• Myoblast 100%
• Oxidative Damage 100%
• Mitochondrial DNA 100%
• Muscular Dystrophy 40%
• Reactive Oxygen Species 40%
• Myotubes 40%
• Skeletal muscle 20%
• DNA Damage 20%
• DNA Sequencing 20%
• DNA Double-strand Breaks 20%
• Myogenic Differentiation 20%
• Apoptosis 20%
• Ectopic Expression 20%
• Highly Sensitive 20%
• Aging 20%
• Skeletal muscle Cells 20%
• Oxygen Consumption 20%
• Skeletal muscle Differentiation 20%
• C2C12 Cells 20%
• Exonuclease 20%
• Cell Resistance 20%
• Myoblast Differentiation 20%
• Mitochondrial Biogenesis 20%
• Oxidative DNA Damage 20%
• Mechanistic Explanation 20%
• Single-strand Break Repair 20%
• Base Excision 20%
• Oxidative Challenge 20%
• Muscle Regeneration 20%
• Mitochondrial Oxidative Phosphorylation 20%
• 5′ End Processing 20%
• Total Glutathione 20%
• High-flow Oxygen 20%
• Myoblast Cells 20%
• Muscle Stem Cell (MuSC) 20%
• Differentiated Products 20%
• Sarcopenia 20%

Biochemistry, Genetics and Molecular Biology

• Skeletal Muscle 100%
• Mitochondrial Genome 100%
• Deficiency 100%
• Myogenesis 25%
• Enzyme 25%
• C2C12 25%
• Programmed Cell Death 25%
• Precursor 25%
• Glutathione 25%
• Ectopic Expression 25%
• DNA Strand 25%
• DNA Damage 25%
• Oxygen Consumption 25%
• Mitochondrial Biogenesis 25%
• Oxidative Phosphorylation 25%
• Muscle Regeneration 25%
• Phosphodiesterase I 25%