Dectin-1-activated dendritic cells: A potent Th9 cell inducer for tumor immunotherapy

Jintong Chen; Yinghua Zhao; Xiao Chu; Yong Lu; Siqing Wang; Qing Yi

doi:10.1080/2162402X.2016.1238558

Dectin-1-activated dendritic cells: A potent Th9 cell inducer for tumor immunotherapy

Jintong Chen, Yinghua Zhao, Xiao Chu, Yong Lu, Siqing Wang, Qing Yi

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Dendritic cell (DC)-based immunotherapy has great promise for cancer treatment. We have recently demonstrated that dectin-1-activated DCs trigger potent antitumor Th9 cells in vivo. Dectin-1-activated DC-induced antitumor responses rely on the induced Th9/IL-9. These findings offer new strategies for the development of more effective DC vaccines in tumor immunotherapy.

Original language	English (US)
Article number	e1238558
Journal	OncoImmunology
Volume	5
Issue number	11
DOIs	https://doi.org/10.1080/2162402X.2016.1238558
State	Published - Nov 1 2016

Keywords

Antitumor immunity
Dectin-1
dentritic cells
Th9
Vaccine

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Oncology

Divisions

Medical Oncology

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10.1080/2162402X.2016.1238558

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title = "Dectin-1-activated dendritic cells: A potent Th9 cell inducer for tumor immunotherapy",

abstract = "Dendritic cell (DC)-based immunotherapy has great promise for cancer treatment. We have recently demonstrated that dectin-1-activated DCs trigger potent antitumor Th9 cells in vivo. Dectin-1-activated DC-induced antitumor responses rely on the induced Th9/IL-9. These findings offer new strategies for the development of more effective DC vaccines in tumor immunotherapy.",

keywords = "Antitumor immunity, Dectin-1, dentritic cells, Th9, Vaccine",

author = "Jintong Chen and Yinghua Zhao and Xiao Chu and Yong Lu and Siqing Wang and Qing Yi",

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doi = "10.1080/2162402X.2016.1238558",

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TY - JOUR

T1 - Dectin-1-activated dendritic cells

T2 - A potent Th9 cell inducer for tumor immunotherapy

AU - Chen, Jintong

AU - Zhao, Yinghua

AU - Chu, Xiao

AU - Lu, Yong

AU - Wang, Siqing

AU - Yi, Qing

PY - 2016/11/1

Y1 - 2016/11/1

N2 - Dendritic cell (DC)-based immunotherapy has great promise for cancer treatment. We have recently demonstrated that dectin-1-activated DCs trigger potent antitumor Th9 cells in vivo. Dectin-1-activated DC-induced antitumor responses rely on the induced Th9/IL-9. These findings offer new strategies for the development of more effective DC vaccines in tumor immunotherapy.

AB - Dendritic cell (DC)-based immunotherapy has great promise for cancer treatment. We have recently demonstrated that dectin-1-activated DCs trigger potent antitumor Th9 cells in vivo. Dectin-1-activated DC-induced antitumor responses rely on the induced Th9/IL-9. These findings offer new strategies for the development of more effective DC vaccines in tumor immunotherapy.

KW - Antitumor immunity

KW - Dectin-1

KW - dentritic cells

KW - Th9

KW - Vaccine

UR - https://www.scopus.com/pages/publications/84994852912

UR - https://www.scopus.com/inward/citedby.url?scp=84994852912&partnerID=8YFLogxK

U2 - 10.1080/2162402X.2016.1238558

DO - 10.1080/2162402X.2016.1238558

M3 - Article

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SN - 2162-4011

VL - 5

JO - OncoImmunology

JF - OncoImmunology

IS - 11

M1 - e1238558

ER -

Dectin-1-activated dendritic cells: A potent Th9 cell inducer for tumor immunotherapy

Abstract

Keywords

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