TY - JOUR
T1 - Database Resources of the BIG Data Center in 2018
AU - BIG Data Center Members
AU - Xu, Xingjian
AU - Hao, Lili
AU - Zhu, Junwei
AU - Tang, Bixia
AU - Zhou, Qing
AU - Song, Fuhai
AU - Chen, Tingting
AU - Zhang, Sisi
AU - Dong, Lili
AU - Lan, Li
AU - Sang, Jian
AU - Liang, Fang
AU - Cao, Jiabao
AU - Liu, Fang
AU - Liu, Lin
AU - Wang, Fan
AU - Ma, Yingke
AU - Zhang, Lijuan
AU - Chen, Meili
AU - Tian, Dongmei
AU - Li, Cuiping
AU - Du, Zhenglin
AU - Yuan, Na
AU - Zeng, Jingyao
AU - Zhang, Zhewen
AU - Wang, Jinyue
AU - Shi, Shuo
AU - Zhang, Yadong
AU - Pan, Mengyu
AU - Zou, Dong
AU - Song, Shuhui
AU - Xia, Lin
AU - Wang, Zhennan
AU - Li, Man
AU - Niu, Guangyi
AU - Zhang, Yang
AU - Sheng, Xin
AU - Lu, Mingming
AU - Wang, Qi
AU - Xiao, Jingfa
AU - Li, Mengwei
AU - Sun, Shixiang
AU - Li, Rujiao
AU - Yu, Chunlei
AU - Wang, Guangyu
AU - Yin, Hongyan
AU - Chen, Huanxin
AU - Sun, Yubin
AU - Yu, Lei
AU - Zhai, Shuang
N1 - Funding Information:
Programs for High Technology Research and Development [863 Program; 2015AA020108 to Z.Z.; 2015AA020101 to F.G.]; National Natural Science Foundation of China [31100915 to L.H.; 31200978 to L.M.; 31771465 and 31471248 to J.X.; 31671360 to Y.X.; 31571358 to F.G.]; International Partnership Program of the Chinese Academy of Sciences [153F11KYSB20160008]; Key Program of the Chinese Academy of Sciences [KJZD-EW-L14 to J.X.]; Key Technology Talent Program of the Chinese Academy of Sciences [to W.Z.]; The 100 Talent Program of the Chinese Academy of Sciences [to Y.B. and Z.Z.]; The Youth Innovation Promotion Association of the Chinese Academy of Sciences [2017141 to S.S.]; The Special Project on Precision Medicine under the National Key R&D Program [SQ2017YFSF090210 to Y.X.]. Funding for open access charge: Strategic Priority Research Program of the Chinese Academy of Sciences. Conflict of interest statement. None declared.
Funding Information:
Strategic Priority Research Program of the Chinese Academy of Sciences [XDB13040500 to W.Z. and Z.Z.; XDA08020102 to Z.Z.]; National Key Research Program of China [2017YFC0907502 to Z.Z.; 2016YFC0901603 to W.Z.; 2017YFC0907503, 2016YFB0201702, 2016YFC0901903 to J.X.]; National
Funding Information:
We thank a number of users for submitting data, providing annotations, sending suggestions and reporting bugs. The BIG Data Center is indebted to its funders, including the Chinese Academy of Sciences, the Ministry of Science and Technology of China, the Natural Science Foundation of China, and Beijing Institute of Genomics.
Publisher Copyright:
© The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.
Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2018/1/1
Y1 - 2018/1/1
N2 - The BIG Data Center at Beijing Institute of Genomics (BIG) of the Chinese Academy of Sciences provides freely open access to a suite of database resources in support of worldwide research activities in both academia and industry. With the vast amounts of omics data generated at ever-greater scales and rates, the BIG Data Center is continually expanding, updating and enriching its core database resources through big-data integration and value-added curation, including BioCode (a repository archiving bioinformatics tool codes), BioProject (a biological project library), BioSample (a biological sample library), Genome Sequence Archive (GSA, a data repository for archiving raw sequence reads), Genome Warehouse (GWH, a centralized resource housing genome-scale data), Genome Variation Map (GVM, a public repository of genome variations), Gene Expression Nebulas (GEN, a database of gene expression profiles based on RNA-Seq data), Methylation Bank (MethBank, an integrated databank of DNA methylomes), and Science Wikis (a series of biological knowledge wikis for community annotations). In addition, three featured web services are provided, viz., BIG Search (search as a service; a scalable inter-domain text search engine), BIG SSO (single sign-on as a service; a user access control system to gain access to multiple independent systems with a single ID and password) and Gsub (submission as a service; a unified submission service for all relevant resources). All of these resources are publicly accessible through the home page of the BIG Data Center at http://bigd.big.ac.cn.
AB - The BIG Data Center at Beijing Institute of Genomics (BIG) of the Chinese Academy of Sciences provides freely open access to a suite of database resources in support of worldwide research activities in both academia and industry. With the vast amounts of omics data generated at ever-greater scales and rates, the BIG Data Center is continually expanding, updating and enriching its core database resources through big-data integration and value-added curation, including BioCode (a repository archiving bioinformatics tool codes), BioProject (a biological project library), BioSample (a biological sample library), Genome Sequence Archive (GSA, a data repository for archiving raw sequence reads), Genome Warehouse (GWH, a centralized resource housing genome-scale data), Genome Variation Map (GVM, a public repository of genome variations), Gene Expression Nebulas (GEN, a database of gene expression profiles based on RNA-Seq data), Methylation Bank (MethBank, an integrated databank of DNA methylomes), and Science Wikis (a series of biological knowledge wikis for community annotations). In addition, three featured web services are provided, viz., BIG Search (search as a service; a scalable inter-domain text search engine), BIG SSO (single sign-on as a service; a user access control system to gain access to multiple independent systems with a single ID and password) and Gsub (submission as a service; a unified submission service for all relevant resources). All of these resources are publicly accessible through the home page of the BIG Data Center at http://bigd.big.ac.cn.
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U2 - 10.1093/nar/gkx897
DO - 10.1093/nar/gkx897
M3 - Article
C2 - 29036542
AN - SCOPUS:85040996048
SN - 0305-1048
VL - 46
SP - D14-D20
JO - Nucleic Acids Research
JF - Nucleic Acids Research
IS - D1
ER -