Abstract
We report a patient with cyclic thrombocytopenia and antiplatelet antibodies, a variant of chronic immune thrombocytopenic purpura (ITP), with a several year history of periodic fluctuation of the platelet count, megakaryocytic hyperplasia and high-titer anti-GPIb-specific antiplatelet antibodies. The patient was resistant to multiple forms of therapy but has responded to the thrombopoietic growth factor, pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF). This case suggests that some patients with classic ITP may respond to thrombopoietic growth factors.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 210-214 |
| Number of pages | 5 |
| Journal | American Journal of Hematology |
| Volume | 68 |
| Issue number | 3 |
| DOIs | |
| State | Published - 2001 |
Keywords
- Antiplatelet antibody
- Cyclic thrombocytopenia
- ITP
- Thrombopoietin
ASJC Scopus subject areas
- Hematology
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