Current status on vascular substitutes

Anne Lejay, Vincenzo Vento, Salomé Kuntz, Lydie Steinmetz, Yannick Georg, Fabien Thaveau, Frédéric Heim, Nabil Chakfé

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations


In the last decades, the main evolution in the field of vascular surgery was correlated to the development and introduction of vascular substitutes. Currently, two types of synthetic vascular substitutes have been widely adopted: polyethylene terephthalate and expanded polytetrafluoroethylene. Ideally, they should demonstrate a behavior as close as possible as that of human arteries in terms of mechanical and biological properties. However, no vascular substitute has been found to compare with the patency rates of gold-standard autologous conduits, and major drawbacks of current vascular substitutes remain both thrombogenicity and infectability.

Original languageEnglish (US)
Pages (from-to)538-543
Number of pages6
JournalJournal of Cardiovascular Surgery
Issue number5
StatePublished - Oct 2020


  • Blood vessel prosthesis
  • Infections
  • Thrombosis

ASJC Scopus subject areas

  • Surgery
  • Cardiology and Cardiovascular Medicine


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