Current and future transcatheter aortic valve replacement valves

Rachel Eikelboom, Ricky Muller Moran, Weiang Yan, Michael Yamashita, Apurva Patel, Michael Reardon, Aaron Spooner

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations


Purpose of reviewThis review analyzes currently available commercial transcatheter aortic valve replacement (TAVR) valves as well as valves in investigational status and those in preclinical testing. The design features and clinical outcomes of the Edwards SAPIEN S3 and Medtronic Evolut PRO+ are described and compared with highlight clinical circumstances where one may be favoured over the other.Recent findingsMultiple randomized and nonrandomized trials have compared commercial and investigational TAVR valves. The results of these are summarized and discussed within this review with a focus on how the SAPIEN S3 and Evolut PRO+ both compare to each other as well as various valves in different investigational stages.SummaryTAVR is an innovative and ground-breaking technology that will forever have revolutionized the management of aortic stenosis. Though the technology and valves themselves have come a long way, further developments are necessary if we are to continue to expand its indications and achieve a safer perioperative experience with more durable valves.

Original languageEnglish (US)
Pages (from-to)173-179
Number of pages7
JournalCurrent Opinion in Cardiology
Issue number2
StatePublished - Mar 1 2022


  • innovation
  • structural heart
  • transcatheter aortic valve implantation
  • transcatheter aortic valve replacement
  • transcatheter heart valve
  • Transcatheter Aortic Valve Replacement
  • Heart Valve Prosthesis
  • Humans
  • Treatment Outcome
  • Prosthesis Design
  • Aortic Valve Stenosis/surgery
  • Aortic Valve/surgery
  • Retrospective Studies

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


Dive into the research topics of 'Current and future transcatheter aortic valve replacement valves'. Together they form a unique fingerprint.

Cite this