Current and future applications of CT coronary calcium assessment

Christian Tesche, Taylor M. Duguay, U. Joseph Schoepf, Marly van Assen, Carlo N. De Cecco, Moritz H. Albrecht, Akos Varga-Szemes, Richard R. Bayer, Ullrich Ebersberger, John W. Nance, Christian Thilo

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations


Introduction: Computed tomographic (CT) coronary artery calcium scoring (CAC) has been validated as a well-established screening method for cardiovascular risk stratification and treatment management that is used in addition to traditional risk factors. The purpose of this review is to present an update on current and future applications of CAC. Areas covered: The topic of CAC is summarized from its introduction to current application with focus on the validation and clinical integration including cardiovascular risk prediction and outcome, cost-effectiveness, impact on downstream medical testing, and the technical advances in scanner and software technology that are shaping the future of CAC. Furthermore, this review aims to provide guidance for the appropriate clinical use of CAC. Expert commentary: CAC is a well-established screening test in preventive care that is underused in daily clinical practice. The widespread clinical implementation of CAC will be decided by future technical advances in CT image acquisition, cost-effectiveness, and reimbursement status.

Original languageEnglish (US)
Pages (from-to)441-453
Number of pages13
JournalExpert Review of Cardiovascular Therapy
Issue number6
StatePublished - Jun 3 2018


  • Computed tomography
  • coronary artery calcium scoring
  • outcome
  • radiation dose
  • risk prediction

ASJC Scopus subject areas

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine


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