Abstract
Established medications that improve tremor include beta-adrenergic antagonists, primidone, topiramate, and ethanol. Less consistent efficacy is reported with many other medications, usually antiepileptic drugs. A number of investigational medications, including T-type calcium channel blockers and allosteric gamma-aminobutyric acid-A modulators, are being developed for tremor. Deep brain stimulation techniques continues to be refined and focused ultrasound thalamotomy now offers an incisionless surgical option. Finally a number of peripheral electrical and mechanical devices are under development for tremor.
Original language | English (US) |
---|---|
Pages (from-to) | 309-323 |
Number of pages | 15 |
Journal | Neurologic Clinics |
Volume | 38 |
Issue number | 2 |
DOIs | |
State | Published - May 2020 |
Keywords
- Botulinum toxin
- Deep brain stimulation
- Essential tremor
- Thalamotomy
- Treatment
- Tremor
- Humans
- Essential Tremor/drug therapy
ASJC Scopus subject areas
- Clinical Neurology