Curing hepatocellular carcinomatosis with biologic therapy and surgery: Achieving the impossible?

Melanie B. Thomas, Eric Tetzlaff, Richard Lozano, Leigh Samp, Charles E. Butler, Christopher Gannon, Stanley Hamilton, Jean Nicholas Vauthey, Eddie Abdalla

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Hepatocellular carcinoma (HCC) that present as hemoperitoneum are uncommon, often recur as peritoneal carcinomatosis, and have poor prognosis. Systemic chemotherapies are minimally effective in advanced HCC and less so as neo-adjuvant therapy. This report describes a 47-year woman with ruptured HCC who developed recurrent carcinomatosis. She received biologically targeted systemic therapy which resulted in significant radiographic tumor response. Salvage surgery revealed complete pathologic response in all tumor nodules, thus the patient was rendered cancer-free.

Original languageEnglish (US)
Pages (from-to)82-84
Number of pages3
JournalJournal of Surgical Oncology
Volume97
Issue number1
DOIs
StatePublished - Jan 1 2008

Keywords

  • Hepatocellular carcinoma
  • Resection
  • Targeted chemotherapy

ASJC Scopus subject areas

  • Surgery
  • Oncology

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