@inbook{655d1956f4754cf3bda7e614a57dde83,
title = "Culturing and expansion of {"}clinical grade{"} precursors cells from the fetal human central nervous system",
abstract = "NSCs have been demonstrated to be very useful in grafts into the mammalian central nervous system to investigate the exploitation of NSC for the therapy of neurodegenerative disorders in animal models of neurodegenerative diseases. To push cell therapy in CNS on stage of clinical application, it is necessary to establish a continuous and standardized, clinical grade (i.e., produced following the good manufacturing practice guidelines) human neural stem cell lines. In this chapter, we illustrate some of the protocols routinely used into our GMP cell bank for the production of {"}clinical grade{"} human neural stem cell lines.",
keywords = "Clinical grade, Good manufacturing practice, Human central nervous system, Neural stem cells, Precursor cells, Therapy",
author = "Maurizio Gelati and Daniela Profico and Massimo Projetti-Pensi and Gianmarco Muzi and Giada Sgaravizzi and Angelo Vescovi",
year = "2013",
month = jan,
day = "1",
doi = "10.1007/978-1-62703-574-3_6",
language = "English (US)",
isbn = "9781627035736",
series = "Methods in Molecular Biology",
publisher = "Humana Press",
pages = "65--77",
booktitle = "Neural Progenitor Cells",
address = "United States",
}