Culture Proven Multi-Bacterial Gastrointestinal Infections are Rare in Children

Richard Kellermayer; Savini L. Britto; Rohan N. Britto; David A. Simon; Reka G. Szigeti; James J. Dunn

doi:10.1097/INF.0000000000004935

Culture Proven Multi-Bacterial Gastrointestinal Infections are Rare in Children

Richard Kellermayer, Savini L. Britto, Rohan N. Britto, David A. Simon, Reka G. Szigeti, James J. Dunn

Research output: Contribution to journal › Article › peer-review

Abstract

We analyzed 6256 pediatric stool cultures and found that 11.4% were positive, with declining positivity rates as the age of the tested patients increased. Multipositive stool cultures (0.05%) occurred only in children ≤3.1 years, all of whom had prior antibiotic use. These findings underscore age-related gut defense maturation and highlight the importance of prudent antibiotic stewardship in early childhood.

Original language	English (US)
Pages (from-to)	e463-e464
Journal	Pediatric Infectious Disease Journal
Volume	44
Issue number	12
Early online date	Aug 6 2025
DOIs	https://doi.org/10.1097/INF.0000000000004935
State	E-pub ahead of print - Aug 6 2025

Keywords

Salmonella
aging
gastroenteritis
pediatric
stool culture

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Microbiology (medical)
Infectious Diseases

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10.1097/INF.0000000000004935

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title = "Culture Proven Multi-Bacterial Gastrointestinal Infections are Rare in Children",

abstract = "We analyzed 6256 pediatric stool cultures and found that 11.4\% were positive, with declining positivity rates as the age of the tested patients increased. Multipositive stool cultures (0.05\%) occurred only in children ≤3.1 years, all of whom had prior antibiotic use. These findings underscore age-related gut defense maturation and highlight the importance of prudent antibiotic stewardship in early childhood.",

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AU - Simon, David A.

AU - Szigeti, Reka G.

AU - Dunn, James J.

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N2 - We analyzed 6256 pediatric stool cultures and found that 11.4% were positive, with declining positivity rates as the age of the tested patients increased. Multipositive stool cultures (0.05%) occurred only in children ≤3.1 years, all of whom had prior antibiotic use. These findings underscore age-related gut defense maturation and highlight the importance of prudent antibiotic stewardship in early childhood.

AB - We analyzed 6256 pediatric stool cultures and found that 11.4% were positive, with declining positivity rates as the age of the tested patients increased. Multipositive stool cultures (0.05%) occurred only in children ≤3.1 years, all of whom had prior antibiotic use. These findings underscore age-related gut defense maturation and highlight the importance of prudent antibiotic stewardship in early childhood.

KW - Salmonella

KW - aging

KW - gastroenteritis

KW - pediatric

KW - stool culture

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JO - Pediatric Infectious Disease Journal

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ER -

Culture Proven Multi-Bacterial Gastrointestinal Infections are Rare in Children

Abstract

Keywords

ASJC Scopus subject areas

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